PYRIDINE COMPOUND

PROBLEM TO BE SOLVED: To obtain a pyridine compound having selectively excellent antimictibial action and gastric acid secretion-suppressing action on Halicobacter pylori and useful as an antiulcer agent hardly causing adverse effects or an agent for preventing recrudescence and relapse of ulcer. SO...

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Bibliographische Detailangaben
Hauptverfasser: SANO MITSUHARU, SAKURAI NOBUHIRO, KAWAKITA TAKESHI, IKEDA TAKASHI
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To obtain a pyridine compound having selectively excellent antimictibial action and gastric acid secretion-suppressing action on Halicobacter pylori and useful as an antiulcer agent hardly causing adverse effects or an agent for preventing recrudescence and relapse of ulcer. SOLUTION: This pyridine compound is represented by formula I R is H, a halogen, etc.; R and R are each H, an alkyl, an alkoxy, etc.; R is COOR , etc.; R is an alkyl, a haloalkyl, etc.; D is a cycloalkyl, a group, etc., expressed by formula II; R and R are each an acyl, etc.; E is an alkylene; Z and Y are each CH or N; (p) or (q) are each 0, 1 or 2; (m) is an integer of 1-1000}, e.g. 2-((3-methyl-4-(2-(2-(2,2,2-trifluoroethoxy)ethoxy)ethylsulfanyl)-2- pyridyl)methylsulfanyl)-1Hbenzimidazole. The compound of formula I is preferably jointly used with an antiulcer medicine, an antibiotic or an antiprotozoan medicine.