PRODUCTION OF TETRAHYDROFURFURYL CARBAMATE DERIVATIVE
PROBLEM TO BE SOLVED: To simply obtain a tetrahydrofurfuryl carbamate derivative which is useful as a preventive and therapeutic agent for AIDS (acquired immunodeficiency syndrome) by acid-treating a specific tetrahydrofurfuryl carbamate derivative to effect selective removal of an acetyl group. SOL...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | YANAGI TAKASHI TAKEUCHI HIDEKI KAMIJO TETSUKIYO YAMAGUCHI TOSHIAKI TSUCHIYA IKUO |
| description | PROBLEM TO BE SOLVED: To simply obtain a tetrahydrofurfuryl carbamate derivative which is useful as a preventive and therapeutic agent for AIDS (acquired immunodeficiency syndrome) by acid-treating a specific tetrahydrofurfuryl carbamate derivative to effect selective removal of an acetyl group. SOLUTION: A tetrahydrofurfuryl carbamate derivative of formula I (the configuration of each C atom marked with (R) is R configuration, while (S) means S configuration) is treated with an acid (for example, a mineral acid such as hydrochloric acid or sulfuric acid, a solution of hydrogen chloride in an alcohol, preferably hydrochloric acid) at 0-120 deg.C, preferably at 20-80 deg.C, for 1-8 hours to give the derivative of formula II. The compound of formula I is obtained by reaction of a corresponding phenylbutanol derivative with 4- acetamidebenzenesulfonic acid or its reactive functional derivative. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_JPH0971574A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>JPH0971574A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_JPH0971574A3</originalsourceid><addsrcrecordid>eNrjZDANCPJ3CXUO8fT3U_B3UwhxDQly9Ih0CfJ3Cw0CokgfBWfHICdHX8cQVwUX1yDPMMcQzzBXHgbWtMSc4lReKM3NoODmGuLsoZtakB-fWlyQmJyal1oS7xXgYWBpbmhqbuJoTIQSAOkVKBI</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>PRODUCTION OF TETRAHYDROFURFURYL CARBAMATE DERIVATIVE</title><source>esp@cenet</source><creator>YANAGI TAKASHI ; TAKEUCHI HIDEKI ; KAMIJO TETSUKIYO ; YAMAGUCHI TOSHIAKI ; TSUCHIYA IKUO</creator><creatorcontrib>YANAGI TAKASHI ; TAKEUCHI HIDEKI ; KAMIJO TETSUKIYO ; YAMAGUCHI TOSHIAKI ; TSUCHIYA IKUO</creatorcontrib><description>PROBLEM TO BE SOLVED: To simply obtain a tetrahydrofurfuryl carbamate derivative which is useful as a preventive and therapeutic agent for AIDS (acquired immunodeficiency syndrome) by acid-treating a specific tetrahydrofurfuryl carbamate derivative to effect selective removal of an acetyl group. SOLUTION: A tetrahydrofurfuryl carbamate derivative of formula I (the configuration of each C atom marked with (R) is R configuration, while (S) means S configuration) is treated with an acid (for example, a mineral acid such as hydrochloric acid or sulfuric acid, a solution of hydrogen chloride in an alcohol, preferably hydrochloric acid) at 0-120 deg.C, preferably at 20-80 deg.C, for 1-8 hours to give the derivative of formula II. The compound of formula I is obtained by reaction of a corresponding phenylbutanol derivative with 4- acetamidebenzenesulfonic acid or its reactive functional derivative.</description><edition>6</edition><language>eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>1997</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19970318&DB=EPODOC&CC=JP&NR=H0971574A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25544,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19970318&DB=EPODOC&CC=JP&NR=H0971574A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>YANAGI TAKASHI</creatorcontrib><creatorcontrib>TAKEUCHI HIDEKI</creatorcontrib><creatorcontrib>KAMIJO TETSUKIYO</creatorcontrib><creatorcontrib>YAMAGUCHI TOSHIAKI</creatorcontrib><creatorcontrib>TSUCHIYA IKUO</creatorcontrib><title>PRODUCTION OF TETRAHYDROFURFURYL CARBAMATE DERIVATIVE</title><description>PROBLEM TO BE SOLVED: To simply obtain a tetrahydrofurfuryl carbamate derivative which is useful as a preventive and therapeutic agent for AIDS (acquired immunodeficiency syndrome) by acid-treating a specific tetrahydrofurfuryl carbamate derivative to effect selective removal of an acetyl group. SOLUTION: A tetrahydrofurfuryl carbamate derivative of formula I (the configuration of each C atom marked with (R) is R configuration, while (S) means S configuration) is treated with an acid (for example, a mineral acid such as hydrochloric acid or sulfuric acid, a solution of hydrogen chloride in an alcohol, preferably hydrochloric acid) at 0-120 deg.C, preferably at 20-80 deg.C, for 1-8 hours to give the derivative of formula II. The compound of formula I is obtained by reaction of a corresponding phenylbutanol derivative with 4- acetamidebenzenesulfonic acid or its reactive functional derivative.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1997</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDANCPJ3CXUO8fT3U_B3UwhxDQly9Ih0CfJ3Cw0CokgfBWfHICdHX8cQVwUX1yDPMMcQzzBXHgbWtMSc4lReKM3NoODmGuLsoZtakB-fWlyQmJyal1oS7xXgYWBpbmhqbuJoTIQSAOkVKBI</recordid><startdate>19970318</startdate><enddate>19970318</enddate><creator>YANAGI TAKASHI</creator><creator>TAKEUCHI HIDEKI</creator><creator>KAMIJO TETSUKIYO</creator><creator>YAMAGUCHI TOSHIAKI</creator><creator>TSUCHIYA IKUO</creator><scope>EVB</scope></search><sort><creationdate>19970318</creationdate><title>PRODUCTION OF TETRAHYDROFURFURYL CARBAMATE DERIVATIVE</title><author>YANAGI TAKASHI ; TAKEUCHI HIDEKI ; KAMIJO TETSUKIYO ; YAMAGUCHI TOSHIAKI ; TSUCHIYA IKUO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_JPH0971574A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1997</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>YANAGI TAKASHI</creatorcontrib><creatorcontrib>TAKEUCHI HIDEKI</creatorcontrib><creatorcontrib>KAMIJO TETSUKIYO</creatorcontrib><creatorcontrib>YAMAGUCHI TOSHIAKI</creatorcontrib><creatorcontrib>TSUCHIYA IKUO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>YANAGI TAKASHI</au><au>TAKEUCHI HIDEKI</au><au>KAMIJO TETSUKIYO</au><au>YAMAGUCHI TOSHIAKI</au><au>TSUCHIYA IKUO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PRODUCTION OF TETRAHYDROFURFURYL CARBAMATE DERIVATIVE</title><date>1997-03-18</date><risdate>1997</risdate><abstract>PROBLEM TO BE SOLVED: To simply obtain a tetrahydrofurfuryl carbamate derivative which is useful as a preventive and therapeutic agent for AIDS (acquired immunodeficiency syndrome) by acid-treating a specific tetrahydrofurfuryl carbamate derivative to effect selective removal of an acetyl group. SOLUTION: A tetrahydrofurfuryl carbamate derivative of formula I (the configuration of each C atom marked with (R) is R configuration, while (S) means S configuration) is treated with an acid (for example, a mineral acid such as hydrochloric acid or sulfuric acid, a solution of hydrogen chloride in an alcohol, preferably hydrochloric acid) at 0-120 deg.C, preferably at 20-80 deg.C, for 1-8 hours to give the derivative of formula II. The compound of formula I is obtained by reaction of a corresponding phenylbutanol derivative with 4- acetamidebenzenesulfonic acid or its reactive functional derivative.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_JPH0971574A |
| source | esp@cenet |
| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE |
| title | PRODUCTION OF TETRAHYDROFURFURYL CARBAMATE DERIVATIVE |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-27T23%3A10%3A55IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=YANAGI%20TAKASHI&rft.date=1997-03-18&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EJPH0971574A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |