PHARMACEUTICAL PREPARATION FOR ORAL ADMINISTRATION

PURPOSE:To obtain a peroral pharmaceutical preparation, containing ultrafine powder of a specific phosphonic acid diester derivative as an active ingredient, having stable and high bioavailability and useful as a pharmaceutical preparation for treating hyperlipemia. CONSTITUTION:This pharmaceutical...

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Hauptverfasser: OBATA HIDEKI, ARITA SHIGEAKI
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creator OBATA HIDEKI
ARITA SHIGEAKI
description PURPOSE:To obtain a peroral pharmaceutical preparation, containing ultrafine powder of a specific phosphonic acid diester derivative as an active ingredient, having stable and high bioavailability and useful as a pharmaceutical preparation for treating hyperlipemia. CONSTITUTION:This pharmaceutical preparation contains ultrafine powder (preferably having
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CONSTITUTION:This pharmaceutical preparation contains ultrafine powder (preferably having &lt;=5mum average particle diameter measured by a microscopic image processor) of a diphosphonic acid diester derivative expressed by the formula (R is a lower alkyl; X is a halogen) {preferably diethyl 4-[(4-bromo-2- cyanophenyl)carbamoyl]benzylphosphonate} as an active ingredient. A powder, a fine granule, a granule, a capsule, a tablet, a syrup, etc., are cited as the form and the daily dose thereof is preferably 0.05-80mg/kg.</description><edition>6</edition><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>1995</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19951107&amp;DB=EPODOC&amp;CC=JP&amp;NR=H07291869A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19951107&amp;DB=EPODOC&amp;CC=JP&amp;NR=H07291869A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>OBATA HIDEKI</creatorcontrib><creatorcontrib>ARITA SHIGEAKI</creatorcontrib><title>PHARMACEUTICAL PREPARATION FOR ORAL ADMINISTRATION</title><description>PURPOSE:To obtain a peroral pharmaceutical preparation, containing ultrafine powder of a specific phosphonic acid diester derivative as an active ingredient, having stable and high bioavailability and useful as a pharmaceutical preparation for treating hyperlipemia. 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CONSTITUTION:This pharmaceutical preparation contains ultrafine powder (preferably having &lt;=5mum average particle diameter measured by a microscopic image processor) of a diphosphonic acid diester derivative expressed by the formula (R is a lower alkyl; X is a halogen) {preferably diethyl 4-[(4-bromo-2- cyanophenyl)carbamoyl]benzylphosphonate} as an active ingredient. A powder, a fine granule, a granule, a capsule, a tablet, a syrup, etc., are cited as the form and the daily dose thereof is preferably 0.05-80mg/kg.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record>
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title PHARMACEUTICAL PREPARATION FOR ORAL ADMINISTRATION
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