PRODUCTION OF D-PROLINE

PURPOSE:To industrially produce D-proline used as a synthetic raw material for medicines, agrochemicals, etc. CONSTITUTION:This method for producing D-proline is to bring a microbial cell of a microorganism, belonging to the genus Escherichia and having proline racemase activities, a culture solutio...

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Bibliographische Detailangaben
Hauptverfasser:	AZUMA MASAYUKI, ISHINO SHUICHI, OZAKI AKIO, YAGASAKI MAKOTO, HASHIMOTO YUKIO
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	PURPOSE:To industrially produce D-proline used as a synthetic raw material for medicines, agrochemicals, etc. CONSTITUTION:This method for producing D-proline is to bring a microbial cell of a microorganism, belonging to the genus Escherichia and having proline racemase activities, a culture solution or a treated substance thereof into contact with L-proline in an aqueous medium, produce DL-proline, then bring the DL- proline produced in the aqueous medium into contact with a microbial cell of a microorganism having L-proline hydrolytic abilities, a culture solution or a treated substance thereof, hydrolyze the L-proline in the aqueous medium and then collect the residual D-proline from the aqueous medium.