PREPARATION OF SLOW RELEASE SOLID PHARMACEUTICALS

PURPOSE: To obtain a drug excellent in storage stability and persisting property by applying a regenerated and aqueous dispersion liquid of a specified binder on the core containing the effective substance. CONSTITUTION: An aqueous dispersion liquid of a binder is obtd. by emulsion polymn. with a pharmaceutically allowed material such as methylmethacrylate. The obtd. dispersion liquid, a water-soluble and pharmaceutically allowed spray assistant having >=60 deg.C glass transition temp. such as methylcellulose by 5 to 50 wt.% of the binder, and a pharmaceutically allowed adhesion preventive such as talc by 0 to 50 wt.% are spray-dried together and then again prepared as a regenerated and aqueous dispersion liquid. The obtd. liquid is applied on the core containing the effective substance to obtain the drug of the purpose.