PREVENTING OR TREATING AGENT FOR PNEUMONIA

PURPOSE:To obtain an agent for the prevention and treatment of pneumonia, effective for noninfectious pneumonia intractable by conventional treating agent and having low side effect by using a 3-phenylthiomethylstyrene derivative as an active component. CONSTITUTION:The objective agent contains, as...

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Hauptverfasser: YAGAWA KATSURO, HAYASHI SHINICHIRO, SHIRAISHI TADAYOSHI
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creator YAGAWA KATSURO
HAYASHI SHINICHIRO
SHIRAISHI TADAYOSHI
description PURPOSE:To obtain an agent for the prevention and treatment of pneumonia, effective for noninfectious pneumonia intractable by conventional treating agent and having low side effect by using a 3-phenylthiomethylstyrene derivative as an active component. CONSTITUTION:The objective agent contains, as an active component, the compound of formula I [X is H, R O (R is 1-3C alkyl), 1-5C alkyl, NO2, NH2, OH, halogen or COOR (R is R ) ; R'' is H, 1-3C alkyl or R CO (R is phenyl or 1-3C alkyl); R is H or 1-5C alkyl; R is COOR (R is H or 1-4C alkyl) or amide; R is CN or R SO2 (R is 1-4C alkyl); R and R may together form group of formula II to formula TV (R is R ; Y is O or NH)], preferably the compound of formula V (R is H, R is CONH2 and R is CN), e.g. alpha-cyano-3- ethoxy-4-hydroxy-5-phenylthiomethyl cinnamic acid amide.
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CONSTITUTION:The objective agent contains, as an active component, the compound of formula I [X is H, R O (R is 1-3C alkyl), 1-5C alkyl, NO2, NH2, OH, halogen or COOR (R is R ) ; R'' is H, 1-3C alkyl or R CO (R is phenyl or 1-3C alkyl); R is H or 1-5C alkyl; R is COOR (R is H or 1-4C alkyl) or amide; R is CN or R SO2 (R is 1-4C alkyl); R and R may together form group of formula II to formula TV (R is R ; Y is O or NH)], preferably the compound of formula V (R is H, R is CONH2 and R is CN), e.g. alpha-cyano-3- ethoxy-4-hydroxy-5-phenylthiomethyl cinnamic acid amide.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1993</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19930108&amp;DB=EPODOC&amp;CC=JP&amp;NR=H05938A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19930108&amp;DB=EPODOC&amp;CC=JP&amp;NR=H05938A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>YAGAWA KATSURO</creatorcontrib><creatorcontrib>HAYASHI SHINICHIRO</creatorcontrib><creatorcontrib>SHIRAISHI TADAYOSHI</creatorcontrib><title>PREVENTING OR TREATING AGENT FOR PNEUMONIA</title><description>PURPOSE:To obtain an agent for the prevention and treatment of pneumonia, effective for noninfectious pneumonia intractable by conventional treating agent and having low side effect by using a 3-phenylthiomethylstyrene derivative as an active component. 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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PREVENTING OR TREATING AGENT FOR PNEUMONIA
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