AMIDOBENZENES

The invention concerns novel phenoxy- and phenylthio-acetyl derivatives of (4-amino-2,6-dimethylphenylsulphonyl)nitromethane and pharmaceutically acceptable salts thereof which are inhibitors of the enzyme aldose reductase and are of value, for example, in the treatment of certain peripheral effects...

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Hauptverfasser: DEEBITSUDO ROBAATO BURITSUTEIN, SUTEIIBUN POORU BURAUN, RINDA SUREITAA, ANSONII ROOREN KUUPAA, JIYON PURESUTON, JIESURO ROURENSU RONGURITSUJI, JIEFUREI JIEEMUZU MOORISU
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creator DEEBITSUDO ROBAATO BURITSUTEIN
SUTEIIBUN POORU BURAUN
RINDA SUREITAA
ANSONII ROOREN KUUPAA
JIYON PURESUTON
JIESURO ROURENSU RONGURITSUJI
JIEFUREI JIEEMUZU MOORISU
description The invention concerns novel phenoxy- and phenylthio-acetyl derivatives of (4-amino-2,6-dimethylphenylsulphonyl)nitromethane and pharmaceutically acceptable salts thereof which are inhibitors of the enzyme aldose reductase and are of value, for example, in the treatment of certain peripheral effects of diabetes and galactosemia. Also disclosed are pharmaceutical compositions containing one of the derivatives and processes for the manufacture and use of the derivatives.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title AMIDOBENZENES
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