SKIN EXTERNAL PREPARATION

PURPOSE:To obtain a skin external preparation excellent in percutaneous absorption property, stability and safety by blending a lipid microsphere containing an active substance. CONSTITUTION:The aimed skin external preparation obtained blending a lipid microsphere having a membrane each containing a...

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Hauptverfasser: YOKOTE TOSHIHARU, NAKADA SATORU, NAKAHIRA MEI
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creator YOKOTE TOSHIHARU
NAKADA SATORU
NAKAHIRA MEI
description PURPOSE:To obtain a skin external preparation excellent in percutaneous absorption property, stability and safety by blending a lipid microsphere containing an active substance. CONSTITUTION:The aimed skin external preparation obtained blending a lipid microsphere having a membrane each containing an active substance and oil as an oil phase inside and phospholipid (e.g. lecithin) outside and being globular particles having about
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CONSTITUTION:The aimed skin external preparation obtained blending a lipid microsphere having a membrane each containing an active substance and oil as an oil phase inside and phospholipid (e.g. lecithin) outside and being globular particles having about &lt;=1mum size. The above mentioned blend is preferably carried out at a ratio of 1-30wt.% phospholipid and 0.1-4wt.% active substance based on the oil. The lipid microsphere enhances percutaneous absorption as well as ribosome and is stable for long term, compared with the ribosome and readily mass-produced.</description><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>1991</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19910418&amp;DB=EPODOC&amp;CC=JP&amp;NR=H0393733A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19910418&amp;DB=EPODOC&amp;CC=JP&amp;NR=H0393733A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>YOKOTE TOSHIHARU</creatorcontrib><creatorcontrib>NAKADA SATORU</creatorcontrib><creatorcontrib>NAKAHIRA MEI</creatorcontrib><title>SKIN EXTERNAL PREPARATION</title><description>PURPOSE:To obtain a skin external preparation excellent in percutaneous absorption property, stability and safety by blending a lipid microsphere containing an active substance. CONSTITUTION:The aimed skin external preparation obtained blending a lipid microsphere having a membrane each containing an active substance and oil as an oil phase inside and phospholipid (e.g. lecithin) outside and being globular particles having about &lt;=1mum size. The above mentioned blend is preferably carried out at a ratio of 1-30wt.% phospholipid and 0.1-4wt.% active substance based on the oil. 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CONSTITUTION:The aimed skin external preparation obtained blending a lipid microsphere having a membrane each containing an active substance and oil as an oil phase inside and phospholipid (e.g. lecithin) outside and being globular particles having about &lt;=1mum size. The above mentioned blend is preferably carried out at a ratio of 1-30wt.% phospholipid and 0.1-4wt.% active substance based on the oil. The lipid microsphere enhances percutaneous absorption as well as ribosome and is stable for long term, compared with the ribosome and readily mass-produced.</abstract><oa>free_for_read</oa></addata></record>
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title SKIN EXTERNAL PREPARATION
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