PYRANOBENZOXADIAZOLE DERIVATIVE

NEW MATERIAL:The compound of formula I [A is OH or OC(O)CH3-nXn (X is F, Cl, Br, methyl or methoxy; n is 0-3); B is H or together with A form a bond; when R is H, R is H, C(Z)CH3-nXn (Z is O or S), etc., and when R is not H, R and R together form (CH2)m (m is 4 or 5), (CH2)m-1C(Z), etc.]. EXAMPLE:7,...

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Hauptverfasser:	MATSUMOTO HIROO, SAKOTA RYOZO, MASUDA YUKINORI, KAMIKAWAJI MASUMASA, IKUYORI KAZUHIKO, NAKAYAMA KIYOUKO, SETO KIYOTOMO
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	NEW MATERIAL:The compound of formula I [A is OH or OC(O)CH3-nXn (X is F, Cl, Br, methyl or methoxy; n is 0-3); B is H or together with A form a bond; when R is H, R is H, C(Z)CH3-nXn (Z is O or S), etc., and when R is not H, R and R together form (CH2)m (m is 4 or 5), (CH2)m-1C(Z), etc.]. EXAMPLE:7,8-Dihydro-6,6-dimethyl-7-hydroxy-8-methylureido-6H-pyrano[2,3- f]benz-2,1,3-oxadiazole of formula II. USE:A remedy for hypertension and asthma. PREPARATION:A compound of formula I wherein both R and R are H and A is OH can be produced by reacting a compound of formula III with ammonia.