DRUG CONTAINING N-(2-PYRIDYL)-2- METHYL-4-HYDROXY-2H-1,2-BENZOTHIAZIN- 3-CARBOOXAMIDE-1,1-DIOXIDE AND PREPARATION THEREOF

DRUG CONTAINING N-(2-PYRIDYL)-2- METHYL-4-HYDROXY-2H-1,2-BENZOTHIAZIN- 3-CARBOOXAMIDE-1,1-DIOXIDE AND PREPARATION THEREOF

PURPOSE: To obtain a homogenized material containing piroxicam finely pulverized to a specific particle diameter, a spray-dried lactose having a specific diameter, a disintegrant, etc., and giving a capsule and tablet having optimum solubility and qualitative parameter. CONSTITUTION: This drug is pr...

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Hauptverfasser: PAARU FUEKETE, KATARIN ZUKOBUICHIYU NEEE SHIYUUMEGU, YAANOSHIYU TOMUBORU, ISHIYUTOBUAAN SHIMONII, DEENESHIYU BETSUZEGU, BIBORUKA MAROSHIYUHERII NEEE KOBUAACHIYU
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator PAARU FUEKETE
KATARIN ZUKOBUICHIYU NEEE SHIYUUMEGU
YAANOSHIYU TOMUBORU
ISHIYUTOBUAAN SHIMONII
DEENESHIYU BETSUZEGU
BIBORUKA MAROSHIYUHERII NEEE KOBUAACHIYU
description PURPOSE: To obtain a homogenized material containing piroxicam finely pulverized to a specific particle diameter, a spray-dried lactose having a specific diameter, a disintegrant, etc., and giving a capsule and tablet having optimum solubility and qualitative parameter. CONSTITUTION: This drug is produced by compounding a mixture composed of (A) 1 pt.wt. of piroxicam containing >=90wt.% of a fraction having particle diameter of
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CONSTITUTION: This drug is produced by compounding a mixture composed of (A) 1 pt.wt. of piroxicam containing &gt;=90wt.% of a fraction having particle diameter of &lt;=30μm, preferably &lt;=10μm and optionally (B) 0.1-5.0 pts.wt. of mannitol having the diameter the same as above and (C) 0.005-0.15 pt.wt. of silica having the diameter the same as above with (D) 5-25 pts.wt. of a spray- dried lactose containing &gt;=80wt.% of a fraction having a particle diameter of 80-200μm and optionally (E) 0.5-6.0 pts.wt. of a disintegrant, preferably starch, (F) 0.005-0.05 pt.wt. of a surfactant, preferably sodium laurylsulfate and (G) 0.05-0.5 pt.wt. of a lubricant, preferably magnesium stearate, homogenizing the obtained mixture and filling the homogenized product in a capsule of forming in the form of a tablet.</description><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1990</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19900704&amp;DB=EPODOC&amp;CC=JP&amp;NR=H02172918A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19900704&amp;DB=EPODOC&amp;CC=JP&amp;NR=H02172918A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PAARU FUEKETE</creatorcontrib><creatorcontrib>KATARIN ZUKOBUICHIYU NEEE SHIYUUMEGU</creatorcontrib><creatorcontrib>YAANOSHIYU TOMUBORU</creatorcontrib><creatorcontrib>ISHIYUTOBUAAN SHIMONII</creatorcontrib><creatorcontrib>DEENESHIYU BETSUZEGU</creatorcontrib><creatorcontrib>BIBORUKA MAROSHIYUHERII NEEE KOBUAACHIYU</creatorcontrib><title>DRUG CONTAINING N-(2-PYRIDYL)-2- METHYL-4-HYDROXY-2H-1,2-BENZOTHIAZIN- 3-CARBOOXAMIDE-1,1-DIOXIDE AND PREPARATION THEREOF</title><description>PURPOSE: To obtain a homogenized material containing piroxicam finely pulverized to a specific particle diameter, a spray-dried lactose having a specific diameter, a disintegrant, etc., and giving a capsule and tablet having optimum solubility and qualitative parameter. 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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title DRUG CONTAINING N-(2-PYRIDYL)-2- METHYL-4-HYDROXY-2H-1,2-BENZOTHIAZIN- 3-CARBOOXAMIDE-1,1-DIOXIDE AND PREPARATION THEREOF
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