REMEDY FOR PANCREATITIS CONTAINING PROSTAGLANDIN-ANALOG COMPOUND AS ACTIVE COMPONENT

PURPOSE:To obtain the subject remedy having cell-protecting action and extremely low toxicity by using a compound such as 15-(3-ethylcyclobutyl-16,17,18,19,20- pentanor-6-oxo-PGE1 as an active component. CONSTITUTION:The objective remedy contains a prostaglandin-analog compound of formula I or formu...

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Bibliographische Detailangaben
Hauptverfasser: IMAKI KATSUHIRO, MURYORIN TAKASHI, SAKAI YOSHINORI
Format: Patent
Sprache:eng
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Zusammenfassung:PURPOSE:To obtain the subject remedy having cell-protecting action and extremely low toxicity by using a compound such as 15-(3-ethylcyclobutyl-16,17,18,19,20- pentanor-6-oxo-PGE1 as an active component. CONSTITUTION:The objective remedy contains a prostaglandin-analog compound of formula I or formula II (R is H or 1-12C straight or branched alkyl; R is H or 1-6C straight or branched alkyl; ...X-Y-Z is group of formula III, formula IV, formula V, etc.; when ...X-Y-Z is the group of formula IV, the configuration of 5- and 6-site is S-, R- or their mixture; when it is the group of formula V, the double bond between 5- and 6-sites has E-configuration, Z-configuration or their mixture; n is 3-5), or when R1 is H, a non-toxic salt of the acid, or their cyclodextrin clathrate component, as an active component. It can be administered by oral or parenteral administration.