PYRANOBENZOXADIAZOLE DERIVATIVE

NEW MATERIAL:A compound expressed by formula I [X and X are not present or O; a represents OH, OC(O)R (R represents 1-4C alkyl) or single bond together with B; B represents H or single bond together with A; R and R represent H, 1-4C alkyl or (substituted)1,4-butylene, etc., by both R and R together;...

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Hauptverfasser: MATSUMOTO HIROO, SAKOTA RYOZO, MASUDA YUKINORI, IKUSE KAZUHIKO, KAMIKAWAJI MASUMASA, NAKAYAMA KIYOUKO, SETO KIYOTOMO
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creator MATSUMOTO HIROO
SAKOTA RYOZO
MASUDA YUKINORI
IKUSE KAZUHIKO
KAMIKAWAJI MASUMASA
NAKAYAMA KIYOUKO
SETO KIYOTOMO
description NEW MATERIAL:A compound expressed by formula I [X and X are not present or O; a represents OH, OC(O)R (R represents 1-4C alkyl) or single bond together with B; B represents H or single bond together with A; R and R represent H, 1-4C alkyl or (substituted)1,4-butylene, etc., by both R and R together; R and R represent H, (substituted) 1-4C alkyl, 3-6C cyclic alkyl, etc.] or salt thereof. EXAMPLE:7,8-Dihydro-6,6-dimethyl-7-hydroxy-8-diethylamino-6H-pyrono[2,3- f]benzo-2,1,3-oxadiazole-3-oxide expressed by formula II. USE:A remedy for hypertension and asthma. PREPARATION:A compound expressed by formula III is reacted with a compound expressed by the formula HN(R )(R ) to afford a compound expressed by formula I wherein both R and R will not represent acyl group.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PYRANOBENZOXADIAZOLE DERIVATIVE
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