NOVEL 1-ARYLSULFONYL-2-PYRROLIDINONE DERIVATIVE, PRODUCTION THEREOF, OBTAINED NOVEL INTERMEDIATE, USE THEREOF AS DRUG AND COMPOSITION CONTAINING THE SAME

The invention relates to the compounds of formula (I): in which R represents where R1 is either (C1-8) alkyl, or denotes where R2 and R3 are hydrogen, (C1-8) alkyl or, together with N, represent a heterocycle optionally containing another hetero atom, or denotes NO2, or OR' where R' is hyd...

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Hauptverfasser: JIYURIO GARURIANI, EMIRIO TOOYA, MISHIERU FUORUTAN, KARURO GORINI, FUERUNANDO BARUTSUAGI
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creator JIYURIO GARURIANI
EMIRIO TOOYA
MISHIERU FUORUTAN
KARURO GORINI
FUERUNANDO BARUTSUAGI
description The invention relates to the compounds of formula (I): in which R represents where R1 is either (C1-8) alkyl, or denotes where R2 and R3 are hydrogen, (C1-8) alkyl or, together with N, represent a heterocycle optionally containing another hetero atom, or denotes NO2, or OR' where R' is hydrogen, (C1-8) alkyl or aryl, or denotes SR4 or S(O)R5 where R4 and R5 are (C1-8) alkyl, or alternatively R represents a naphthyl optionally substituted with R'1, R'1 having the meanings stated for R1, to a process for their preparation, to their use as medicaments which are useful in the treatment of various spasmodic disorders and to pharmaceutical compositions containing them.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title NOVEL 1-ARYLSULFONYL-2-PYRROLIDINONE DERIVATIVE, PRODUCTION THEREOF, OBTAINED NOVEL INTERMEDIATE, USE THEREOF AS DRUG AND COMPOSITION CONTAINING THE SAME
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