DETECTION DEVICE

To provide a detection device that enables highly accurate visual checking of presence or absence of fluorescence in a fluorescent immunochromatographic method.SOLUTION: A detection device is a detection device for detecting a target substance by a fluorescent immunochromatographic method, and the d...

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Hauptverfasser: YOKOYAMA MASAFUMI, TAKEISHI TAKAAKI
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creator YOKOYAMA MASAFUMI
TAKEISHI TAKAAKI
description To provide a detection device that enables highly accurate visual checking of presence or absence of fluorescence in a fluorescent immunochromatographic method.SOLUTION: A detection device is a detection device for detecting a target substance by a fluorescent immunochromatographic method, and the detection device has: a package that holds a cassette accommodating a membrane containing a fluorescent particle bonded with the target substance via an antibody; a light source that is accommodated in the package, and irradiates the membrane with excitation light exciting the fluorescent particle; and an optical filter that transmits fluorescence to be radiated from the excited fluorescent particle to enable a naked eye to observe from outside of the package. A center wavelength of a transmission wavelength range of the optical filter is a wavelength on a 555 nm side with respect to a peak wavelength of the fluorescence, and an intensity ratio of the fluorescence transmitting the optical filter to self-fluorescence of the membrane transmitting the optical filter is set to the wavelength to be larger than the intensity ratio in a case where the center wavelength is equal to the peak wavelength.SELECTED DRAWING: Figure 1 【課題】蛍光イムノクロマト法において、高精度に蛍光の有無を目視確認することを可能とする検出装置を提供する。【解決手段】検出装置は、蛍光イムノクロマト法により標的物質を検出するための検出装置であって、抗体を介して標的物質と結合した蛍光粒子を含有するメンブレンを収容するカセットを保持するパッケージと、パッケージに収容され、蛍光粒子を励起させる励起光をメンブレンに照射する光源と、励起された蛍光粒子から放射される蛍光を透過させてパッケージの外部から肉眼で観察可能とする光学フィルタと、を有し、光学フィルタの透過波長域の中心波長は、蛍光のピーク波長に対して555nmの側の波長であって、光学フィルタを透過したメンブレンの自家蛍光に対する光学フィルタを透過した蛍光の強度比が、中心波長がピーク波長と等しい場合の強度比よりも大きくなるような波長に設定される。【選択図】図1
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subjects INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
title DETECTION DEVICE
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