PHARMACEUTICAL COMPOSITION INCLUDING NOVEL ANTI-PAD4 ANTIBODY

To provide a pharmaceutical composition including an anti-PAD4 antibody or an antibody fragment thereof having excellent properties.SOLUTION: A pharmaceutical composition including an anti-PAD4 antibody or an antibody fragment thereof is provided in which HCDR1 includes an amino acid sequence of SEQ...

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Hauptverfasser: WADA KOICHI, SAKATA TOMOKO, SHIGEMITSU TAKANARI, IMURA YUICHI, SAITO KENJI, MIYAMOTO YUYA
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creator WADA KOICHI
SAKATA TOMOKO
SHIGEMITSU TAKANARI
IMURA YUICHI
SAITO KENJI
MIYAMOTO YUYA
description To provide a pharmaceutical composition including an anti-PAD4 antibody or an antibody fragment thereof having excellent properties.SOLUTION: A pharmaceutical composition including an anti-PAD4 antibody or an antibody fragment thereof is provided in which HCDR1 includes an amino acid sequence of SEQ ID NO: 1, HCDR2 includes an amino acid sequence of SEQ ID NO: 2, HCDR3 includes an amino acid sequence of SEQ ID NO: 3, LCDR1 includes an amino acid sequence of SEQ ID NO: 4, LCDR2 includes an amino acid sequence of SEQ ID NO: 5, and LCDR3 includes an amino acid sequence of SEQ ID NO: 6.SELECTED DRAWING: Figure 1 【課題】優れた特性を有する抗PAD4抗体又はその抗体断片を含む医薬組成物を提供すること。【解決手段】HCDR1が配列番号1のアミノ酸配列を含み、HCDR2が配列番号2のアミノ酸配列を含み、HCDR3が配列番号3のアミノ酸配列を含み、LCDR1が配列番号4のアミノ酸配列を含み、LCDR2が配列番号5のアミノ酸配列を含み、LCDR3が配列番号6のアミノ酸配列を含む、抗PAD4抗体又はその抗体断片、を含む医薬組成物、を提供する。【選択図】図1
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PHARMACEUTICAL COMPOSITION INCLUDING NOVEL ANTI-PAD4 ANTIBODY
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