MESOTHELIN AND CD137 BINDING MOLECULES

To solve the problem in which clinical development of CD137 agonist molecules has been held back because of treatment being associated with either dose-limiting high-grade liver inflammation (urelumab) or low clinical efficacy (utomilumab).SOLUTION: The present invention relates to antibody molecule...

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Hauptverfasser:	JOSE MUNOZ-OLAYA, FRANCISCA WOLLERTON, NEIL BREWIS, REMI FERTIN, CLAIRE READER, MIHRIBAN TUNA
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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