METHOD FOR PRODUCING PYRIDINE COMPOUND
To provide a novel method for producing a pyridine compound useful as a precursor of a heterocyclic amide compound useful as a herbicide.SOLUTION: There is provided a method for producing a pyridine compound represented by the formula (1), which comprises: a step of reacting a cyanoacetate ester com...
Gespeichert in:
Hauptverfasser: | , , |
---|---|
Format: | Patent |
Sprache: | eng ; jpn |
Schlagworte: | |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | To provide a novel method for producing a pyridine compound useful as a precursor of a heterocyclic amide compound useful as a herbicide.SOLUTION: There is provided a method for producing a pyridine compound represented by the formula (1), which comprises: a step of reacting a cyanoacetate ester compound represented by the formula (2) with an enone compound represented by the formula (3) in the presence of a base, followed by cyclization reaction by acid treatment to form a pyridine compound represented by the formula (1); a step of extracting the resulting reaction product into an aqueous layer, followed by re-extracting into an organic layer; and a step of purifying the reaction product. (wherein, R1 represents an alkyl group having 1 to 3 carbon atoms and R2 represents an alkyl group having 1 to 4 carbon atoms.)SELECTED DRAWING: None
【課題】除草剤として有用な複素環アミド化合物の前駆体として有用な、ピリジン化合物の新規な製造方法を提供する。【解決手段】式(1)で表されるピリジン化合物の製造方法であって、式(2)で表されるシアノ酢酸エステル化合物を式(3)で表されるエノン化合物に塩基の存在下で反応させ、次いで酸処理により環化反応を行い、式(1)で表されるピリジン化合物を生成させる工程、並びに、得られた反応生成物を水層に抽出した後、有機層に再抽出する工程を含むことを特徴とする、反応生成物の精製工程とを含む、製造方法。JPEG2023132937000008.jpg50159(式中、R1はC数1~3のアルキル基、R2はC数1~4のアルキル基を表す。)【選択図】なし |
---|