SPECIMEN INSPECTION METHOD, SPECIMEN INSPECTION KIT, AND SPECIMEN INSPECTION DEVICE
To provide a technique regarding an antigen inspection capable of detecting a detection object in a specimen with high sensitivity.SOLUTION: A specimen inspection device according to an embodiment has an optical measurement part and a determination part. The optical measurement part allows light to...
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| creator | MOMOZAKI SATORU YOSHIMURA SAIKO |
| description | To provide a technique regarding an antigen inspection capable of detecting a detection object in a specimen with high sensitivity.SOLUTION: A specimen inspection device according to an embodiment has an optical measurement part and a determination part. The optical measurement part allows light to enter an optical waveguide provided in an inspection vessel via a sensor area, and measures intensity of light propagated through the optical waveguide and emitted from the optical waveguide. The determination part determines whether a specimen dropped to the inspection vessel contains a detection object on the basis of light intensity. A first affinity substance having affinity to the detection object is fixed in the sensor area, and a second affinity substance having affinity to the detection object is added to the inspection vessel. A first primer is bonded to the first affinity substance and/or a second primer is bonded to the second affinity substance. The determination part performs determination on the basis of a change in intensity of light by an amplification product generated by an amplification reaction with the first primer and/or the second primer as a starting point.SELECTED DRAWING: Figure 11
【課題】 検体中の検出対象を高い感度で検出することができる抗原検査に関する技術を提供すること。【解決手段】 実施形態に係る検体検査装置は、光学測定部と判定部とを具備する。光学測定部は、検査容器にセンサエリアを介して設けられた光導波路に光を入射し、光導波路を伝播して光導波路から出射された光の強度を測定する。判定部は、光の強度に基づいて検査容器に滴下された検体に検出対象が含まれるか否かを判定する。センサエリアには、検出対象に対して親和性を有する第１親和性物質が固定され、検査容器に、検出対象に対して親和性を有する第２親和性物質が添加される。第１親和性物質に第１プライマーが結合しており、及び／又は第２親和性物質に第２プライマーが結合している。判定部は、第１プライマー及び／又は第２プライマーを起点とした増幅反応により生成された増幅産物による光の強度の変化に基づいて判定する。【選択図】 図１１ |
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【課題】 検体中の検出対象を高い感度で検出することができる抗原検査に関する技術を提供すること。【解決手段】 実施形態に係る検体検査装置は、光学測定部と判定部とを具備する。光学測定部は、検査容器にセンサエリアを介して設けられた光導波路に光を入射し、光導波路を伝播して光導波路から出射された光の強度を測定する。判定部は、光の強度に基づいて検査容器に滴下された検体に検出対象が含まれるか否かを判定する。センサエリアには、検出対象に対して親和性を有する第１親和性物質が固定され、検査容器に、検出対象に対して親和性を有する第２親和性物質が添加される。第１親和性物質に第１プライマーが結合しており、及び／又は第２親和性物質に第２プライマーが結合している。判定部は、第１プライマー及び／又は第２プライマーを起点とした増幅反応により生成された増幅産物による光の強度の変化に基づいて判定する。【選択図】 図１１</description><language>eng ; jpn</language><subject>APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY ; BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; ENZYMOLOGY ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; PHYSICS ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; SPIRITS ; TESTING ; VINEGAR ; WINE</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230523&DB=EPODOC&CC=JP&NR=2023071397A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230523&DB=EPODOC&CC=JP&NR=2023071397A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MOMOZAKI SATORU</creatorcontrib><creatorcontrib>YOSHIMURA SAIKO</creatorcontrib><title>SPECIMEN INSPECTION METHOD, SPECIMEN INSPECTION KIT, AND SPECIMEN INSPECTION DEVICE</title><description>To provide a technique regarding an antigen inspection capable of detecting a detection object in a specimen with high sensitivity.SOLUTION: A specimen inspection device according to an embodiment has an optical measurement part and a determination part. The optical measurement part allows light to enter an optical waveguide provided in an inspection vessel via a sensor area, and measures intensity of light propagated through the optical waveguide and emitted from the optical waveguide. The determination part determines whether a specimen dropped to the inspection vessel contains a detection object on the basis of light intensity. A first affinity substance having affinity to the detection object is fixed in the sensor area, and a second affinity substance having affinity to the detection object is added to the inspection vessel. A first primer is bonded to the first affinity substance and/or a second primer is bonded to the second affinity substance. The determination part performs determination on the basis of a change in intensity of light by an amplification product generated by an amplification reaction with the first primer and/or the second primer as a starting point.SELECTED DRAWING: Figure 11
【課題】 検体中の検出対象を高い感度で検出することができる抗原検査に関する技術を提供すること。【解決手段】 実施形態に係る検体検査装置は、光学測定部と判定部とを具備する。光学測定部は、検査容器にセンサエリアを介して設けられた光導波路に光を入射し、光導波路を伝播して光導波路から出射された光の強度を測定する。判定部は、光の強度に基づいて検査容器に滴下された検体に検出対象が含まれるか否かを判定する。センサエリアには、検出対象に対して親和性を有する第１親和性物質が固定され、検査容器に、検出対象に対して親和性を有する第２親和性物質が添加される。第１親和性物質に第１プライマーが結合しており、及び／又は第２親和性物質に第２プライマーが結合している。判定部は、第１プライマー及び／又は第２プライマーを起点とした増幅反応により生成された増幅産物による光の強度の変化に基づいて判定する。【選択図】 図１１</description><subject>APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY</subject><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>ENZYMOLOGY</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PHYSICS</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>SPIRITS</subject><subject>TESTING</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZAgODnB19vR19VPw9AMxQzz9_RR8XUM8_F10FLDJeXuG6Cg4-rlglXRxDfN0duVhYE1LzClO5YXS3AxKbq4hzh66qQX58anFBYnJqXmpJfFeAUYGRsYG5obGluaOxkQpAgBdtjBG</recordid><startdate>20230523</startdate><enddate>20230523</enddate><creator>MOMOZAKI SATORU</creator><creator>YOSHIMURA SAIKO</creator><scope>EVB</scope></search><sort><creationdate>20230523</creationdate><title>SPECIMEN INSPECTION METHOD, SPECIMEN INSPECTION KIT, AND SPECIMEN INSPECTION DEVICE</title><author>MOMOZAKI SATORU ; YOSHIMURA SAIKO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_JP2023071397A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; jpn</language><creationdate>2023</creationdate><topic>APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY</topic><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>ENZYMOLOGY</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PHYSICS</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>SPIRITS</topic><topic>TESTING</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>MOMOZAKI SATORU</creatorcontrib><creatorcontrib>YOSHIMURA SAIKO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MOMOZAKI SATORU</au><au>YOSHIMURA SAIKO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SPECIMEN INSPECTION METHOD, SPECIMEN INSPECTION KIT, AND SPECIMEN INSPECTION DEVICE</title><date>2023-05-23</date><risdate>2023</risdate><abstract>To provide a technique regarding an antigen inspection capable of detecting a detection object in a specimen with high sensitivity.SOLUTION: A specimen inspection device according to an embodiment has an optical measurement part and a determination part. The optical measurement part allows light to enter an optical waveguide provided in an inspection vessel via a sensor area, and measures intensity of light propagated through the optical waveguide and emitted from the optical waveguide. The determination part determines whether a specimen dropped to the inspection vessel contains a detection object on the basis of light intensity. A first affinity substance having affinity to the detection object is fixed in the sensor area, and a second affinity substance having affinity to the detection object is added to the inspection vessel. A first primer is bonded to the first affinity substance and/or a second primer is bonded to the second affinity substance. The determination part performs determination on the basis of a change in intensity of light by an amplification product generated by an amplification reaction with the first primer and/or the second primer as a starting point.SELECTED DRAWING: Figure 11
【課題】 検体中の検出対象を高い感度で検出することができる抗原検査に関する技術を提供すること。【解決手段】 実施形態に係る検体検査装置は、光学測定部と判定部とを具備する。光学測定部は、検査容器にセンサエリアを介して設けられた光導波路に光を入射し、光導波路を伝播して光導波路から出射された光の強度を測定する。判定部は、光の強度に基づいて検査容器に滴下された検体に検出対象が含まれるか否かを判定する。センサエリアには、検出対象に対して親和性を有する第１親和性物質が固定され、検査容器に、検出対象に対して親和性を有する第２親和性物質が添加される。第１親和性物質に第１プライマーが結合しており、及び／又は第２親和性物質に第２プライマーが結合している。判定部は、第１プライマー及び／又は第２プライマーを起点とした増幅反応により生成された増幅産物による光の強度の変化に基づいて判定する。【選択図】 図１１</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE |
| title | SPECIMEN INSPECTION METHOD, SPECIMEN INSPECTION KIT, AND SPECIMEN INSPECTION DEVICE |
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