ANALYSIS METHOD FOR PEPTIDE BOUND TO CARRIER FOR LIQUID PHASE PEPTIDE SYNTHESIS

To provide means that makes it possible to simultaneously and accurately analyze a component derived from a carrier for liquid phase peptide synthesis and a target peptide or the like.SOLUTION: Provided is a method for analyzing one or more compounds selected from a carrier for liquid phase peptide...

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Bibliographische Detailangaben
Hauptverfasser: ABE JUN, MORI TOSHIHIRO, NEMOTO YOSHITAKA
Format: Patent
Sprache:eng ; jpn
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Beschreibung
Zusammenfassung:To provide means that makes it possible to simultaneously and accurately analyze a component derived from a carrier for liquid phase peptide synthesis and a target peptide or the like.SOLUTION: Provided is a method for analyzing one or more compounds selected from a carrier for liquid phase peptide synthesis, a component derived from the carrier for liquid phase peptide synthesis, an amino acid to which the carrier for liquid phase peptide synthesis is bound, and a peptide compound to which the carrier for liquid phase peptide synthesis is bound, the method employing high-performance liquid chromatography or supercritical fluid chromatography using an alcohol as an eluent.SELECTED DRAWING: None 【課題】液相ペプチド合成用担体由来の成分と目的ペプチドなどとを同時に正確に分析できる手段を提供すること。【解決手段】アルコール類を溶離液として用いる高速液体クロマトグラフィー又は超臨界流体クロマトグラフィーを用いることを特徴とする、液相ペプチド合成用担体、液相ペプチド合成用担体由来の成分、液相ペプチド合成用担体が結合しているアミノ酸及び液相ペプチド合成用担体が結合しているペプチド化合物から選ばれる1種以上の化合物の分析方法。【選択図】なし