PHARMACEUTICAL COMPOSITIONS CONTAINING ADENO-ASSOCIATED VIRAL VECTOR

To provide stable rAAV vector formulations suitable for clinical administration.SOLUTION: The invention provides a pharmaceutical composition comprising a recombinant AAV (rAAV) vector and one or more pharmaceutically acceptable excipients. The composition has improved stability compared with other...

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Bibliographische Detailangaben
Hauptverfasser:	TAMARA SHAFER HODGE, EKATERINA VASILIEVNA TORRES
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	To provide stable rAAV vector formulations suitable for clinical administration.SOLUTION: The invention provides a pharmaceutical composition comprising a recombinant AAV (rAAV) vector and one or more pharmaceutically acceptable excipients. The composition has improved stability compared with other rAAV compositions. 【課題】臨床投与に適した安定なｒＡＡＶベクター調合物を提供すること。【解決手段】本発明は、組換えＡＡＶ（ｒＡＡＶ）ベクターおよび１つまたは複数の薬学的に許容できる賦形剤を含む組成物を提供する。当該組成物は、他のｒＡＡＶ組成物と比較して安定性が向上している。