FLUORESCENT DYE AND LABELED BIOLOGICAL SUBSTANCE USING THE SAME

To provide a fluorescent dye that can yield a labeled biological material that exhibits excellent fluorescence intensity in any of the states of solution, membrane and dot plot, and to provide a labeled biological substance.SOLUTION: Provided are a fluorescent dye and a labeled biological substance...

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1. Verfasser: KANAZAWA YOSHINORI
Format: Patent
Sprache:eng ; jpn
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Zusammenfassung:To provide a fluorescent dye that can yield a labeled biological material that exhibits excellent fluorescence intensity in any of the states of solution, membrane and dot plot, and to provide a labeled biological substance.SOLUTION: Provided are a fluorescent dye and a labeled biological substance that are represented by the following general formula (I) or (II). In the formula, M represents a t-valent linking group, and t is an integer of 3 or more. L represents a divalent linking group formed by combining at least two of -C≡C-, an arylene group and a heteroarylene group. X represents an ether bond, thioether bond, alkylene group, amide bond, ester bond or amino bond. R indicates a fluophor part.SELECTED DRAWING: None 【課題】溶液、メンブレン及びドットプロットのいずれの状態においても優れた蛍光強度を示す標識生体物質を得ることができる蛍光色素及び標識生体物質を提供する。【解決手段】下記一般式(I)又は(II)で表される蛍光色素及び標識生体物質。TIFF2022131357000041.tif12161式中、Mはt価の連結基を示し、tは3以上の整数である。Lは、-C≡C-、アリーレン基及びヘテロアリーレン基のうちの少なくとも2つを組合わせてなる2価の連結基を示す。Xは、エーテル結合、チオエーテル結合、アルキレン基、アミド結合、エステル結合又はアミノ結合を示す。Rは、蛍光体部を示す。【選択図】なし