CELL CULTURE MEMBER AND METHOD FOR MODIFYING SURFACE THEREOF
To provide cell culture members with an excellent cell culture performance and long-term stability thereof, and to provide methods for modifying a surface thereof.SOLUTION: In the cell culture member according to the present invention, at least a holding region of adhesive cells is consisting of a p...
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Sprache: | eng ; jpn |
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Zusammenfassung: | To provide cell culture members with an excellent cell culture performance and long-term stability thereof, and to provide methods for modifying a surface thereof.SOLUTION: In the cell culture member according to the present invention, at least a holding region of adhesive cells is consisting of a polymer compound. At least a part of the holding region is a surface modification region in which a functional group containing a nitrogen atom is directly chemically bonded to a part of carbon atoms and/or silicon atoms constituting the polymer compound. The cell culture member improves adhesiveness of the adhesive cells with respect to the surface modification region, suppresses deterioration of adhesiveness over time, and has excellent cell culture performance and long-term stability.SELECTED DRAWING: Figure 1
【課題】優れた細胞培養性能、及びその長期安定性を備えた細胞培養部材及びその表面改質方法を提供する。【解決手段】本発明に係る細胞培養部材は、少なくとも接着性細胞の保持領域が高分子化合物からなる細胞培養部材であって、前記保持領域の少なくとも一部は、前記高分子化合物を構成する炭素原子及び/又はケイ素原子の一部に窒素原子を含む官能基が直接化学結合した表面改質領域であることを特徴とし、接着性細胞の表面改質領域に対する接着性を向上させ、接着性の経時劣化を抑制し、細胞培養性能とその長期安定性に優れた細胞培養部材を提供することができる。【選択図】 図1 |
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