CELL CULTURE MEMBER AND METHOD FOR MODIFYING SURFACE THEREOF

To provide cell culture members with an excellent cell culture performance and long-term stability thereof, and to provide methods for modifying a surface thereof.SOLUTION: In the cell culture member according to the present invention, at least a holding region of adhesive cells is consisting of a p...

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Hauptverfasser: NISHIDA TETSUO, SAITO NAOTO, KUNO KAZUTOSHI, UEMURA TAKESHI, FUTAI KEIICHI, YAMAMOTO MASASHI, SATO YOSHINORI
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creator NISHIDA TETSUO
SAITO NAOTO
KUNO KAZUTOSHI
UEMURA TAKESHI
FUTAI KEIICHI
YAMAMOTO MASASHI
SATO YOSHINORI
description To provide cell culture members with an excellent cell culture performance and long-term stability thereof, and to provide methods for modifying a surface thereof.SOLUTION: In the cell culture member according to the present invention, at least a holding region of adhesive cells is consisting of a polymer compound. At least a part of the holding region is a surface modification region in which a fluorine atom is directly chemically bonded to a part of carbon atoms and/or silicon atoms constituting the polymer compound. The cell culture member improves adhesiveness of the adhesive cells with respect to the surface modification region, suppresses deterioration of adhesiveness over time, and has excellent cell culture performance and long-term stability.SELECTED DRAWING: Figure 1 【課題】優れた細胞培養性能、及びその長期安定性を備えた細胞培養部材及びその表面改質方法を提供する。【解決手段】本発明に係る細胞培養部材は、少なくとも接着性細胞の保持領域が高分子化合物からなる細胞培養部材であって、前記保持領域の少なくとも一部は、前記高分子化合物を構成する炭素原子及び/又はケイ素原子の一部にフッ素原子が直接化学結合した表面改質領域であることを特徴とし、接着性細胞の表面改質領域に対する接着性を向上させ、接着性の経時劣化を抑制し、細胞培養性能とその長期安定性に優れた細胞培養部材を提供することができる。【選択図】 図1
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subjects AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F,C08G
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS BASED THEREON
ENZYMOLOGY
GENERAL PROCESSES OF COMPOUNDING
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC MACROMOLECULAR COMPOUNDS
SPIRITS
THEIR PREPARATION OR CHEMICAL WORKING-UP
VINEGAR
WINE
WORKING-UP
title CELL CULTURE MEMBER AND METHOD FOR MODIFYING SURFACE THEREOF
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