ANTIGEN-PRESENTING CELL MIMETIC SCAFFOLD, AND METHOD FOR FABRICATING AND USING THE SAME
To provide a composition and a method in which isolation of a T-cell is made possible, and which can be easily used for treatment of human diseases (e.g., immunodeficiency disorder, autoimmune disorder and cancer).SOLUTION: Provided is a composition and a method for manipulating a T-cell, which is a...
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| creator | MOONEY DAVID J ALEXANDER SING CHEUNG |
| description | To provide a composition and a method in which isolation of a T-cell is made possible, and which can be easily used for treatment of human diseases (e.g., immunodeficiency disorder, autoimmune disorder and cancer).SOLUTION: Provided is a composition and a method for manipulating a T-cell, which is activating, stimulating, enlarging, propagating, or energizing, for example. In this state, an embodiment provides a method for expressing certain kinds of marker and/or cell surface receptor or for generating a large number of (or substantially pure partial population of) activation T-cells which generates certain kinds of cytokine optimum for T-cell-mediated immune response. Such a manipulated T-cell can be used in treatment and prevention of many diseases (e.g., cancer, infectious disease, autoimmune disorder, allergy, immune dysfunction associated with aging, or any other disease states for the treatment of which T-cell is desired).SELECTED DRAWING: None
【課題】ヒトの疾患（例えば、免疫不全障害、自己免疫障害、およびがん）の治療に容易に利用され得る、Ｔ細胞の単離を可能にする組成物および方法を提供する。【解決手段】本発明は、Ｔ細胞を操作する、例えば、活性化する、刺激する、拡大する、増殖させる、または賦活する（ｅｎｅｒｇｉｚｉｎｇ）ための組成物および方法を提供する。この状況では、本発明の実施形態は、ある種のマーカーおよび／もしくは細胞表面レセプターを発現するか、またはＴ細胞媒介性免疫応答に最適なある種のサイトカインを生成する多数の（または実質的に純粋な部分集団の）活性化Ｔ細胞を生成するための方法を提供する。このような操作されたＴ細胞は、多くの疾患（例えば、がん、感染性疾患、自己免疫疾患、アレルギー、加齢に関連得る免疫機能不全、または処置にＴ細胞が望まれる任意の他の疾患状態）の処置および防止において使用され得る。【選択図】なし |
| format | Patent |
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【課題】ヒトの疾患（例えば、免疫不全障害、自己免疫障害、およびがん）の治療に容易に利用され得る、Ｔ細胞の単離を可能にする組成物および方法を提供する。【解決手段】本発明は、Ｔ細胞を操作する、例えば、活性化する、刺激する、拡大する、増殖させる、または賦活する（ｅｎｅｒｇｉｚｉｎｇ）ための組成物および方法を提供する。この状況では、本発明の実施形態は、ある種のマーカーおよび／もしくは細胞表面レセプターを発現するか、またはＴ細胞媒介性免疫応答に最適なある種のサイトカインを生成する多数の（または実質的に純粋な部分集団の）活性化Ｔ細胞を生成するための方法を提供する。このような操作されたＴ細胞は、多くの疾患（例えば、がん、感染性疾患、自己免疫疾患、アレルギー、加齢に関連得る免疫機能不全、または処置にＴ細胞が望まれる任意の他の疾患状態）の処置および防止において使用され得る。【選択図】なし</description><language>eng ; jpn</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220106&DB=EPODOC&CC=JP&NR=2022001069A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25544,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220106&DB=EPODOC&CC=JP&NR=2022001069A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MOONEY DAVID J</creatorcontrib><creatorcontrib>ALEXANDER SING CHEUNG</creatorcontrib><title>ANTIGEN-PRESENTING CELL MIMETIC SCAFFOLD, AND METHOD FOR FABRICATING AND USING THE SAME</title><description>To provide a composition and a method in which isolation of a T-cell is made possible, and which can be easily used for treatment of human diseases (e.g., immunodeficiency disorder, autoimmune disorder and cancer).SOLUTION: Provided is a composition and a method for manipulating a T-cell, which is activating, stimulating, enlarging, propagating, or energizing, for example. In this state, an embodiment provides a method for expressing certain kinds of marker and/or cell surface receptor or for generating a large number of (or substantially pure partial population of) activation T-cells which generates certain kinds of cytokine optimum for T-cell-mediated immune response. Such a manipulated T-cell can be used in treatment and prevention of many diseases (e.g., cancer, infectious disease, autoimmune disorder, allergy, immune dysfunction associated with aging, or any other disease states for the treatment of which T-cell is desired).SELECTED DRAWING: None
【課題】ヒトの疾患（例えば、免疫不全障害、自己免疫障害、およびがん）の治療に容易に利用され得る、Ｔ細胞の単離を可能にする組成物および方法を提供する。【解決手段】本発明は、Ｔ細胞を操作する、例えば、活性化する、刺激する、拡大する、増殖させる、または賦活する（ｅｎｅｒｇｉｚｉｎｇ）ための組成物および方法を提供する。この状況では、本発明の実施形態は、ある種のマーカーおよび／もしくは細胞表面レセプターを発現するか、またはＴ細胞媒介性免疫応答に最適なある種のサイトカインを生成する多数の（または実質的に純粋な部分集団の）活性化Ｔ細胞を生成するための方法を提供する。このような操作されたＴ細胞は、多くの疾患（例えば、がん、感染性疾患、自己免疫疾患、アレルギー、加齢に関連得る免疫機能不全、または処置にＴ細胞が望まれる任意の他の疾患状態）の処置および防止において使用され得る。【選択図】なし</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZAh39AvxdHf10w0Icg12BbL93BWcXX18FHw9fV1DPJ0Vgp0d3dz8fVx0FBz9XBSAYh7-Lgpu_kEKbo5OQZ7OjmAdIKnQYBArxMNVIdjR15WHgTUtMac4lRdKczMoubmGOHvophbkx6cWFyQmp-allsR7BRgZGBkZGBgamFk6GhOlCADcDTC7</recordid><startdate>20220106</startdate><enddate>20220106</enddate><creator>MOONEY DAVID J</creator><creator>ALEXANDER SING CHEUNG</creator><scope>EVB</scope></search><sort><creationdate>20220106</creationdate><title>ANTIGEN-PRESENTING CELL MIMETIC SCAFFOLD, AND METHOD FOR FABRICATING AND USING THE SAME</title><author>MOONEY DAVID J ; ALEXANDER SING CHEUNG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_JP2022001069A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; jpn</language><creationdate>2022</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>MOONEY DAVID J</creatorcontrib><creatorcontrib>ALEXANDER SING CHEUNG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MOONEY DAVID J</au><au>ALEXANDER SING CHEUNG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ANTIGEN-PRESENTING CELL MIMETIC SCAFFOLD, AND METHOD FOR FABRICATING AND USING THE SAME</title><date>2022-01-06</date><risdate>2022</risdate><abstract>To provide a composition and a method in which isolation of a T-cell is made possible, and which can be easily used for treatment of human diseases (e.g., immunodeficiency disorder, autoimmune disorder and cancer).SOLUTION: Provided is a composition and a method for manipulating a T-cell, which is activating, stimulating, enlarging, propagating, or energizing, for example. In this state, an embodiment provides a method for expressing certain kinds of marker and/or cell surface receptor or for generating a large number of (or substantially pure partial population of) activation T-cells which generates certain kinds of cytokine optimum for T-cell-mediated immune response. Such a manipulated T-cell can be used in treatment and prevention of many diseases (e.g., cancer, infectious disease, autoimmune disorder, allergy, immune dysfunction associated with aging, or any other disease states for the treatment of which T-cell is desired).SELECTED DRAWING: None
【課題】ヒトの疾患（例えば、免疫不全障害、自己免疫障害、およびがん）の治療に容易に利用され得る、Ｔ細胞の単離を可能にする組成物および方法を提供する。【解決手段】本発明は、Ｔ細胞を操作する、例えば、活性化する、刺激する、拡大する、増殖させる、または賦活する（ｅｎｅｒｇｉｚｉｎｇ）ための組成物および方法を提供する。この状況では、本発明の実施形態は、ある種のマーカーおよび／もしくは細胞表面レセプターを発現するか、またはＴ細胞媒介性免疫応答に最適なある種のサイトカインを生成する多数の（または実質的に純粋な部分集団の）活性化Ｔ細胞を生成するための方法を提供する。このような操作されたＴ細胞は、多くの疾患（例えば、がん、感染性疾患、自己免疫疾患、アレルギー、加齢に関連得る免疫機能不全、または処置にＴ細胞が望まれる任意の他の疾患状態）の処置および防止において使用され得る。【選択図】なし</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE |
| title | ANTIGEN-PRESENTING CELL MIMETIC SCAFFOLD, AND METHOD FOR FABRICATING AND USING THE SAME |
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