MULTIVALENT VACCINE COMPOSITION
To provide a stable, immunogenic combination vaccine comprising a mixture of antigens for prevention and prophylaxis of infections caused by Rotavirus, Poliomyelitis virus, Haemophilus influenzae, Corynebacterium diphtheriae, Clostridium tetani, Bordetella pertussis and Hepatitis B virus.SOLUTION: T...
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| creator | RAVINDRA BAPURAO KADAM JIANG BAOMING RAJEEV MHALASAKANT DHERE SAMBHAJI SHANKAR PISAL RAJENDRA NARAYAN SABALE JAGDISH KAMALAJI ZADE ABHIJEET SANJEEV KAMBLE ROGER GLASS |
| description | To provide a stable, immunogenic combination vaccine comprising a mixture of antigens for prevention and prophylaxis of infections caused by Rotavirus, Poliomyelitis virus, Haemophilus influenzae, Corynebacterium diphtheriae, Clostridium tetani, Bordetella pertussis and Hepatitis B virus.SOLUTION: The present invention discloses a combination vaccine comprising i) an inactivated polio virus (IPV) antigen selected from Salk or Sabin strain and ii) an inactivated rotavirus (IRV) antigen, wherein the dose-reduced inactivated polio virus antigen is adsorbed on an aluminium hydroxide adjuvant, the adsorption rate of aluminium hydroxide is 70-99%, the rotavirus antigen is a heat-inactivated CDC-9 rotavirus strain and is adsorbed on aluminium hydroxide, and the concentration of the rotavirus antigen is 10 μg/dose.SELECTED DRAWING: None
【課題】ロタウイルス、急性灰白髄炎ウイルス、インフルエンザ菌、ジフテリア菌、破傷風菌、百日咳菌及びB型肝炎ウイルスによって引き起こされる感染症の予防及び防止のための抗原の混合物を含む、安定な免疫原性の混合ワクチンを提供する。【解決手段】ｉ）ソーク又はセービン株から選択される不活性化ポリオウイルス（ＩＰＶ）抗原;ｉｉ）不活性化ロタウイルス（ＩＲＶ）抗原;前記減用量不活化ポリオウイルス抗原が、水酸化アルミニウムアジュバントに吸着され、水酸化アルミニウムの吸着率が、７０〜９９%の範囲であり、前記ロタウイルス抗原が、熱不活化ＣＤＣ−９ロタウイルス株であり、かつ、水酸化アルミニウムに吸着されており、及び前記ロタウイルス抗原の濃度が、１０μｇ／用量である、混合ワクチンである。【選択図】なし |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_JP2021181445A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>JP2021181445A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_JP2021181445A3</originalsourceid><addsrcrecordid>eNrjZJD3DfUJ8Qxz9HH1C1EIc3R29vRzVXD29w3wD_YM8fT342FgTUvMKU7lhdLcDEpuriHOHrqpBfnxqcUFicmpeakl8V4BRgZGhoYWhiYmpo7GRCkCADS-IlQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>MULTIVALENT VACCINE COMPOSITION</title><source>esp@cenet</source><creator>RAVINDRA BAPURAO KADAM ; JIANG BAOMING ; RAJEEV MHALASAKANT DHERE ; SAMBHAJI SHANKAR PISAL ; RAJENDRA NARAYAN SABALE ; JAGDISH KAMALAJI ZADE ; ABHIJEET SANJEEV KAMBLE ; ROGER GLASS</creator><creatorcontrib>RAVINDRA BAPURAO KADAM ; JIANG BAOMING ; RAJEEV MHALASAKANT DHERE ; SAMBHAJI SHANKAR PISAL ; RAJENDRA NARAYAN SABALE ; JAGDISH KAMALAJI ZADE ; ABHIJEET SANJEEV KAMBLE ; ROGER GLASS</creatorcontrib><description>To provide a stable, immunogenic combination vaccine comprising a mixture of antigens for prevention and prophylaxis of infections caused by Rotavirus, Poliomyelitis virus, Haemophilus influenzae, Corynebacterium diphtheriae, Clostridium tetani, Bordetella pertussis and Hepatitis B virus.SOLUTION: The present invention discloses a combination vaccine comprising i) an inactivated polio virus (IPV) antigen selected from Salk or Sabin strain and ii) an inactivated rotavirus (IRV) antigen, wherein the dose-reduced inactivated polio virus antigen is adsorbed on an aluminium hydroxide adjuvant, the adsorption rate of aluminium hydroxide is 70-99%, the rotavirus antigen is a heat-inactivated CDC-9 rotavirus strain and is adsorbed on aluminium hydroxide, and the concentration of the rotavirus antigen is 10 μg/dose.SELECTED DRAWING: None
【課題】ロタウイルス、急性灰白髄炎ウイルス、インフルエンザ菌、ジフテリア菌、破傷風菌、百日咳菌及びB型肝炎ウイルスによって引き起こされる感染症の予防及び防止のための抗原の混合物を含む、安定な免疫原性の混合ワクチンを提供する。【解決手段】ｉ）ソーク又はセービン株から選択される不活性化ポリオウイルス（ＩＰＶ）抗原;ｉｉ）不活性化ロタウイルス（ＩＲＶ）抗原;前記減用量不活化ポリオウイルス抗原が、水酸化アルミニウムアジュバントに吸着され、水酸化アルミニウムの吸着率が、７０〜９９%の範囲であり、前記ロタウイルス抗原が、熱不活化ＣＤＣ−９ロタウイルス株であり、かつ、水酸化アルミニウムに吸着されており、及び前記ロタウイルス抗原の濃度が、１０μｇ／用量である、混合ワクチンである。【選択図】なし</description><language>eng ; jpn</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20211125&DB=EPODOC&CC=JP&NR=2021181445A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20211125&DB=EPODOC&CC=JP&NR=2021181445A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>RAVINDRA BAPURAO KADAM</creatorcontrib><creatorcontrib>JIANG BAOMING</creatorcontrib><creatorcontrib>RAJEEV MHALASAKANT DHERE</creatorcontrib><creatorcontrib>SAMBHAJI SHANKAR PISAL</creatorcontrib><creatorcontrib>RAJENDRA NARAYAN SABALE</creatorcontrib><creatorcontrib>JAGDISH KAMALAJI ZADE</creatorcontrib><creatorcontrib>ABHIJEET SANJEEV KAMBLE</creatorcontrib><creatorcontrib>ROGER GLASS</creatorcontrib><title>MULTIVALENT VACCINE COMPOSITION</title><description>To provide a stable, immunogenic combination vaccine comprising a mixture of antigens for prevention and prophylaxis of infections caused by Rotavirus, Poliomyelitis virus, Haemophilus influenzae, Corynebacterium diphtheriae, Clostridium tetani, Bordetella pertussis and Hepatitis B virus.SOLUTION: The present invention discloses a combination vaccine comprising i) an inactivated polio virus (IPV) antigen selected from Salk or Sabin strain and ii) an inactivated rotavirus (IRV) antigen, wherein the dose-reduced inactivated polio virus antigen is adsorbed on an aluminium hydroxide adjuvant, the adsorption rate of aluminium hydroxide is 70-99%, the rotavirus antigen is a heat-inactivated CDC-9 rotavirus strain and is adsorbed on aluminium hydroxide, and the concentration of the rotavirus antigen is 10 μg/dose.SELECTED DRAWING: None
【課題】ロタウイルス、急性灰白髄炎ウイルス、インフルエンザ菌、ジフテリア菌、破傷風菌、百日咳菌及びB型肝炎ウイルスによって引き起こされる感染症の予防及び防止のための抗原の混合物を含む、安定な免疫原性の混合ワクチンを提供する。【解決手段】ｉ）ソーク又はセービン株から選択される不活性化ポリオウイルス（ＩＰＶ）抗原;ｉｉ）不活性化ロタウイルス（ＩＲＶ）抗原;前記減用量不活化ポリオウイルス抗原が、水酸化アルミニウムアジュバントに吸着され、水酸化アルミニウムの吸着率が、７０〜９９%の範囲であり、前記ロタウイルス抗原が、熱不活化ＣＤＣ−９ロタウイルス株であり、かつ、水酸化アルミニウムに吸着されており、及び前記ロタウイルス抗原の濃度が、１０μｇ／用量である、混合ワクチンである。【選択図】なし</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJD3DfUJ8Qxz9HH1C1EIc3R29vRzVXD29w3wD_YM8fT342FgTUvMKU7lhdLcDEpuriHOHrqpBfnxqcUFicmpeakl8V4BRgZGhoYWhiYmpo7GRCkCADS-IlQ</recordid><startdate>20211125</startdate><enddate>20211125</enddate><creator>RAVINDRA BAPURAO KADAM</creator><creator>JIANG BAOMING</creator><creator>RAJEEV MHALASAKANT DHERE</creator><creator>SAMBHAJI SHANKAR PISAL</creator><creator>RAJENDRA NARAYAN SABALE</creator><creator>JAGDISH KAMALAJI ZADE</creator><creator>ABHIJEET SANJEEV KAMBLE</creator><creator>ROGER GLASS</creator><scope>EVB</scope></search><sort><creationdate>20211125</creationdate><title>MULTIVALENT VACCINE COMPOSITION</title><author>RAVINDRA BAPURAO KADAM ; JIANG BAOMING ; RAJEEV MHALASAKANT DHERE ; SAMBHAJI SHANKAR PISAL ; RAJENDRA NARAYAN SABALE ; JAGDISH KAMALAJI ZADE ; ABHIJEET SANJEEV KAMBLE ; ROGER GLASS</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_JP2021181445A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; jpn</language><creationdate>2021</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>RAVINDRA BAPURAO KADAM</creatorcontrib><creatorcontrib>JIANG BAOMING</creatorcontrib><creatorcontrib>RAJEEV MHALASAKANT DHERE</creatorcontrib><creatorcontrib>SAMBHAJI SHANKAR PISAL</creatorcontrib><creatorcontrib>RAJENDRA NARAYAN SABALE</creatorcontrib><creatorcontrib>JAGDISH KAMALAJI ZADE</creatorcontrib><creatorcontrib>ABHIJEET SANJEEV KAMBLE</creatorcontrib><creatorcontrib>ROGER GLASS</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>RAVINDRA BAPURAO KADAM</au><au>JIANG BAOMING</au><au>RAJEEV MHALASAKANT DHERE</au><au>SAMBHAJI SHANKAR PISAL</au><au>RAJENDRA NARAYAN SABALE</au><au>JAGDISH KAMALAJI ZADE</au><au>ABHIJEET SANJEEV KAMBLE</au><au>ROGER GLASS</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>MULTIVALENT VACCINE COMPOSITION</title><date>2021-11-25</date><risdate>2021</risdate><abstract>To provide a stable, immunogenic combination vaccine comprising a mixture of antigens for prevention and prophylaxis of infections caused by Rotavirus, Poliomyelitis virus, Haemophilus influenzae, Corynebacterium diphtheriae, Clostridium tetani, Bordetella pertussis and Hepatitis B virus.SOLUTION: The present invention discloses a combination vaccine comprising i) an inactivated polio virus (IPV) antigen selected from Salk or Sabin strain and ii) an inactivated rotavirus (IRV) antigen, wherein the dose-reduced inactivated polio virus antigen is adsorbed on an aluminium hydroxide adjuvant, the adsorption rate of aluminium hydroxide is 70-99%, the rotavirus antigen is a heat-inactivated CDC-9 rotavirus strain and is adsorbed on aluminium hydroxide, and the concentration of the rotavirus antigen is 10 μg/dose.SELECTED DRAWING: None
【課題】ロタウイルス、急性灰白髄炎ウイルス、インフルエンザ菌、ジフテリア菌、破傷風菌、百日咳菌及びB型肝炎ウイルスによって引き起こされる感染症の予防及び防止のための抗原の混合物を含む、安定な免疫原性の混合ワクチンを提供する。【解決手段】ｉ）ソーク又はセービン株から選択される不活性化ポリオウイルス（ＩＰＶ）抗原;ｉｉ）不活性化ロタウイルス（ＩＲＶ）抗原;前記減用量不活化ポリオウイルス抗原が、水酸化アルミニウムアジュバントに吸着され、水酸化アルミニウムの吸着率が、７０〜９９%の範囲であり、前記ロタウイルス抗原が、熱不活化ＣＤＣ−９ロタウイルス株であり、かつ、水酸化アルミニウムに吸着されており、及び前記ロタウイルス抗原の濃度が、１０μｇ／用量である、混合ワクチンである。【選択図】なし</abstract><oa>free_for_read</oa></addata></record> |
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| title | MULTIVALENT VACCINE COMPOSITION |
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