METHODS FOR TREATING HEPATITIS C
To provide methods for treating hepatitis C virus (HCV) infection.SOLUTION: A method for combined use of an HCV protease inhibitor or HCV polymerase inhibitor and methyl {(2S,3R)-1-[(2S)-2-{5-[(2R,5R)-1-{3,5-difluoro-4-[4-(4-fluorophenyl)piperidin-1-yl]phenyl}-5-(6-fluoro-2-{(2S)-1-[N-(methoxycarbon...
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| creator | TAMI J PILOT-MATIAS THOMAS J REISCH LIU DACHUN WAGNER ROLF MATULENKO MARK A JOHN K PRATT RYAN G KEDDY NEETA C MISTRY WARREN M KATI PREETHI KRISHNAN IOK CHAN NG CLARENCE J MARING |
| description | To provide methods for treating hepatitis C virus (HCV) infection.SOLUTION: A method for combined use of an HCV protease inhibitor or HCV polymerase inhibitor and methyl {(2S,3R)-1-[(2S)-2-{5-[(2R,5R)-1-{3,5-difluoro-4-[4-(4-fluorophenyl)piperidin-1-yl]phenyl}-5-(6-fluoro-2-{(2S)-1-[N-(methoxycarbonyl)-O-methyl-L-threonyl]pyrrolidin-2-yl}-1H-benzimidazol-5-yl)pyrrolidin-2-yl]-6-fluoro-1H-benzimidazol-2-yl}pyrrolidin-1-yl]-3-methoxy-1-oxobutan-2-yl}carbamate.SELECTED DRAWING: None
【課題】Ｃ型肝炎ウイルス（ＨＣＶ）感染を治療する方法の提供。【解決手段】メチル｛（２Ｓ，３Ｒ）−１−［（２Ｓ）−２−｛５−［（２Ｒ，５Ｒ）−１−｛３，５−ジフルオロ−４−［４−（４−フルオロフェニル）ピペリジン−１−イル］フェニル｝−５−（６−フルオロ−２−｛（２Ｓ）−１−［Ｎ−（メトキシカルボニル）−Ｏ−メチル−Ｌ−トレオニル］ピロリジン−２−イル｝−１Ｈ−ベンゾイミダゾール−５−イル）ピロリジン−２−イル］−６−フルオロ−１Ｈ−ベンゾイミダゾール−２−イル｝ピロリジン−１−イル］−３−メトキシ−１−オキソブタン−２−イル｝カルバメートとＨＣＶプロテアーゼ阻害剤またはＨＣＶポリメラーゼ阻害剤とを組み合わせて使用する方法。【選択図】なし |
| format | Patent |
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【課題】Ｃ型肝炎ウイルス（ＨＣＶ）感染を治療する方法の提供。【解決手段】メチル｛（２Ｓ，３Ｒ）−１−［（２Ｓ）−２−｛５−［（２Ｒ，５Ｒ）−１−｛３，５−ジフルオロ−４−［４−（４−フルオロフェニル）ピペリジン−１−イル］フェニル｝−５−（６−フルオロ−２−｛（２Ｓ）−１−［Ｎ−（メトキシカルボニル）−Ｏ−メチル−Ｌ−トレオニル］ピロリジン−２−イル｝−１Ｈ−ベンゾイミダゾール−５−イル）ピロリジン−２−イル］−６−フルオロ−１Ｈ−ベンゾイミダゾール−２−イル｝ピロリジン−１−イル］−３−メトキシ−１−オキソブタン−２−イル｝カルバメートとＨＣＶプロテアーゼ阻害剤またはＨＣＶポリメラーゼ阻害剤とを組み合わせて使用する方法。【選択図】なし</description><language>eng ; jpn</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20191107&DB=EPODOC&CC=JP&NR=2019194241A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20191107&DB=EPODOC&CC=JP&NR=2019194241A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TAMI J PILOT-MATIAS</creatorcontrib><creatorcontrib>THOMAS J REISCH</creatorcontrib><creatorcontrib>LIU DACHUN</creatorcontrib><creatorcontrib>WAGNER ROLF</creatorcontrib><creatorcontrib>MATULENKO MARK A</creatorcontrib><creatorcontrib>JOHN K PRATT</creatorcontrib><creatorcontrib>RYAN G KEDDY</creatorcontrib><creatorcontrib>NEETA C MISTRY</creatorcontrib><creatorcontrib>WARREN M KATI</creatorcontrib><creatorcontrib>PREETHI KRISHNAN</creatorcontrib><creatorcontrib>IOK CHAN NG</creatorcontrib><creatorcontrib>CLARENCE J MARING</creatorcontrib><title>METHODS FOR TREATING HEPATITIS C</title><description>To provide methods for treating hepatitis C virus (HCV) infection.SOLUTION: A method for combined use of an HCV protease inhibitor or HCV polymerase inhibitor and methyl {(2S,3R)-1-[(2S)-2-{5-[(2R,5R)-1-{3,5-difluoro-4-[4-(4-fluorophenyl)piperidin-1-yl]phenyl}-5-(6-fluoro-2-{(2S)-1-[N-(methoxycarbonyl)-O-methyl-L-threonyl]pyrrolidin-2-yl}-1H-benzimidazol-5-yl)pyrrolidin-2-yl]-6-fluoro-1H-benzimidazol-2-yl}pyrrolidin-1-yl]-3-methoxy-1-oxobutan-2-yl}carbamate.SELECTED DRAWING: None
【課題】Ｃ型肝炎ウイルス（ＨＣＶ）感染を治療する方法の提供。【解決手段】メチル｛（２Ｓ，３Ｒ）−１−［（２Ｓ）−２−｛５−［（２Ｒ，５Ｒ）−１−｛３，５−ジフルオロ−４−［４−（４−フルオロフェニル）ピペリジン−１−イル］フェニル｝−５−（６−フルオロ−２−｛（２Ｓ）−１−［Ｎ−（メトキシカルボニル）−Ｏ−メチル−Ｌ−トレオニル］ピロリジン−２−イル｝−１Ｈ−ベンゾイミダゾール−５−イル）ピロリジン−２−イル］−６−フルオロ−１Ｈ−ベンゾイミダゾール−２−イル｝ピロリジン−１−イル］−３−メトキシ−１−オキソブタン−２−イル｝カルバメートとＨＣＶプロテアーゼ阻害剤またはＨＣＶポリメラーゼ阻害剤とを組み合わせて使用する方法。【選択図】なし</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFDwdQ3x8HcJVnDzD1IICXJ1DPH0c1fwcA0AMkI8gxWceRhY0xJzilN5oTQ3g5Kba4izh25qQX58anFBYnJqXmpJvFeAkYGhpaGliZGJoaMxUYoAMTYiRA</recordid><startdate>20191107</startdate><enddate>20191107</enddate><creator>TAMI J PILOT-MATIAS</creator><creator>THOMAS J REISCH</creator><creator>LIU DACHUN</creator><creator>WAGNER ROLF</creator><creator>MATULENKO MARK A</creator><creator>JOHN K PRATT</creator><creator>RYAN G KEDDY</creator><creator>NEETA C MISTRY</creator><creator>WARREN M KATI</creator><creator>PREETHI KRISHNAN</creator><creator>IOK CHAN NG</creator><creator>CLARENCE J MARING</creator><scope>EVB</scope></search><sort><creationdate>20191107</creationdate><title>METHODS FOR TREATING HEPATITIS C</title><author>TAMI J PILOT-MATIAS ; THOMAS J REISCH ; LIU DACHUN ; WAGNER ROLF ; MATULENKO MARK A ; JOHN K PRATT ; RYAN G KEDDY ; NEETA C MISTRY ; WARREN M KATI ; PREETHI KRISHNAN ; IOK CHAN NG ; CLARENCE J MARING</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_JP2019194241A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; jpn</language><creationdate>2019</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>TAMI J PILOT-MATIAS</creatorcontrib><creatorcontrib>THOMAS J REISCH</creatorcontrib><creatorcontrib>LIU DACHUN</creatorcontrib><creatorcontrib>WAGNER ROLF</creatorcontrib><creatorcontrib>MATULENKO MARK A</creatorcontrib><creatorcontrib>JOHN K PRATT</creatorcontrib><creatorcontrib>RYAN G KEDDY</creatorcontrib><creatorcontrib>NEETA C MISTRY</creatorcontrib><creatorcontrib>WARREN M KATI</creatorcontrib><creatorcontrib>PREETHI KRISHNAN</creatorcontrib><creatorcontrib>IOK CHAN NG</creatorcontrib><creatorcontrib>CLARENCE J MARING</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>TAMI J PILOT-MATIAS</au><au>THOMAS J REISCH</au><au>LIU DACHUN</au><au>WAGNER ROLF</au><au>MATULENKO MARK A</au><au>JOHN K PRATT</au><au>RYAN G KEDDY</au><au>NEETA C MISTRY</au><au>WARREN M KATI</au><au>PREETHI KRISHNAN</au><au>IOK CHAN NG</au><au>CLARENCE J MARING</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHODS FOR TREATING HEPATITIS C</title><date>2019-11-07</date><risdate>2019</risdate><abstract>To provide methods for treating hepatitis C virus (HCV) infection.SOLUTION: A method for combined use of an HCV protease inhibitor or HCV polymerase inhibitor and methyl {(2S,3R)-1-[(2S)-2-{5-[(2R,5R)-1-{3,5-difluoro-4-[4-(4-fluorophenyl)piperidin-1-yl]phenyl}-5-(6-fluoro-2-{(2S)-1-[N-(methoxycarbonyl)-O-methyl-L-threonyl]pyrrolidin-2-yl}-1H-benzimidazol-5-yl)pyrrolidin-2-yl]-6-fluoro-1H-benzimidazol-2-yl}pyrrolidin-1-yl]-3-methoxy-1-oxobutan-2-yl}carbamate.SELECTED DRAWING: None
【課題】Ｃ型肝炎ウイルス（ＨＣＶ）感染を治療する方法の提供。【解決手段】メチル｛（２Ｓ，３Ｒ）−１−［（２Ｓ）−２−｛５−［（２Ｒ，５Ｒ）−１−｛３，５−ジフルオロ−４−［４−（４−フルオロフェニル）ピペリジン−１−イル］フェニル｝−５−（６−フルオロ−２−｛（２Ｓ）−１−［Ｎ−（メトキシカルボニル）−Ｏ−メチル−Ｌ−トレオニル］ピロリジン−２−イル｝−１Ｈ−ベンゾイミダゾール−５−イル）ピロリジン−２−イル］−６−フルオロ−１Ｈ−ベンゾイミダゾール−２−イル｝ピロリジン−１−イル］−３−メトキシ−１−オキソブタン−２−イル｝カルバメートとＨＣＶプロテアーゼ阻害剤またはＨＣＶポリメラーゼ阻害剤とを組み合わせて使用する方法。【選択図】なし</abstract><oa>free_for_read</oa></addata></record> |
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| title | METHODS FOR TREATING HEPATITIS C |
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