COMPOSITIONS USED FOR ACE INHIBITION, SUPPRESSION OF BLOOD PRESSURE ELEVATION, OR BLOOD PRESSURE DECREASE, AND METHODS FOR PRODUCING THE SAME
To provide compositions used for angiotensin I converting enzyme (ACE) inhibition, suppression of blood pressure elevation, or blood pressure decrease, and to provide methods for producing the same.SOLUTION: Provided is a composition for ACE inhibition, suppression of blood pressure elevation, or bl...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; jpn |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | NAKANO OSAHISA KUBO NOBUKO YOSHIDA KYOKO MUTSUSHIRO MINORU OZAKI NORIYA |
| description | To provide compositions used for angiotensin I converting enzyme (ACE) inhibition, suppression of blood pressure elevation, or blood pressure decrease, and to provide methods for producing the same.SOLUTION: Provided is a composition for ACE inhibition, suppression of blood pressure elevation, or blood pressure decrease, in which the content of one or more dipeptide compounds selected from arginyl glutamine, glutaminyl arginine, arginyl asparagine, asparaginyl arginine, and salts thereof is 0.10 mg/L or more. The composition for ACE inhibition, suppression of blood pressure elevation, or blood pressure decrease contains a water-soluble component derived from the Euglena cells in which lipid is removed and the dipeptide compound. The composition for ACE inhibition, suppression of blood pressure elevation, or blood pressure decrease contains Euglena cells grown in a medium having a glutamic acid content of 3.4 mmol/L or more and an ammonia nitrogen content of 13 mmol/L or more and dried, or a disrupted product thereof, or the water-soluble component.SELECTED DRAWING: Figure 7
【課題】アンジオテンシンI変換酵素（ＡＣＥ）阻害、血圧上昇抑制、又は血圧降下に用いられる組成物、及びその製造方法の提供。【解決手段】アルギニルグルタミン、グルタミニルアルギニン、アルギニルアスパラギン、アスパラギニルアルギニン、及びこれらの塩から選ばれた１種以上のジペプチド化合物の含有量が０．１０ｍｇ／Ｌ以上である、ＡＣＥ阻害用、血圧上昇抑制用、又は血圧降下用の組成物。ユーグレナ細胞から脂質を除去され前記細胞由来の水溶性成分を含んで前記ジペプチド化合物を含有する、ＡＣＥ阻害用、血圧上昇抑制用、又は血圧降下用の組成物。グルタミン酸の含有量が３．４ｍｍｏｌ／Ｌ以上かつアンモニア態窒素の含有量が１３ｍｍｏｌ／Ｌ以上である培地で生育して乾燥させられたユーグレナ細胞、又はその破砕処理物、もしくは前記水溶性成分を含む、ＡＣＥ阻害用、血圧上昇抑制用、又は血圧降下用の組成物。【選択図】図７ |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_JP2019172674A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>JP2019172674A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_JP2019172674A3</originalsourceid><addsrcrecordid>eNqNjTELwjAUhLs4iPofHs4VbBWLY5q8mojNC3mtaykSJ9FC_Rv-Z0t1cnI67r47bhq9JJWO2FSGLEPNqKAgD0IiGKtNPoIYuHbOI_NggArIT0QKxqT2CHjCs_gUh-0PVCg9CsYYhFVQYqVJ8XjiPKlaGnuASiOwKHEeTa7trQ-Lr86iZYGV1KvQPZrQd-0l3MOzObp0neyTLN1lW7H5q_QGHPNAJQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>COMPOSITIONS USED FOR ACE INHIBITION, SUPPRESSION OF BLOOD PRESSURE ELEVATION, OR BLOOD PRESSURE DECREASE, AND METHODS FOR PRODUCING THE SAME</title><source>esp@cenet</source><creator>NAKANO OSAHISA ; KUBO NOBUKO ; YOSHIDA KYOKO ; MUTSUSHIRO MINORU ; OZAKI NORIYA</creator><creatorcontrib>NAKANO OSAHISA ; KUBO NOBUKO ; YOSHIDA KYOKO ; MUTSUSHIRO MINORU ; OZAKI NORIYA</creatorcontrib><description>To provide compositions used for angiotensin I converting enzyme (ACE) inhibition, suppression of blood pressure elevation, or blood pressure decrease, and to provide methods for producing the same.SOLUTION: Provided is a composition for ACE inhibition, suppression of blood pressure elevation, or blood pressure decrease, in which the content of one or more dipeptide compounds selected from arginyl glutamine, glutaminyl arginine, arginyl asparagine, asparaginyl arginine, and salts thereof is 0.10 mg/L or more. The composition for ACE inhibition, suppression of blood pressure elevation, or blood pressure decrease contains a water-soluble component derived from the Euglena cells in which lipid is removed and the dipeptide compound. The composition for ACE inhibition, suppression of blood pressure elevation, or blood pressure decrease contains Euglena cells grown in a medium having a glutamic acid content of 3.4 mmol/L or more and an ammonia nitrogen content of 13 mmol/L or more and dried, or a disrupted product thereof, or the water-soluble component.SELECTED DRAWING: Figure 7
【課題】アンジオテンシンI変換酵素（ＡＣＥ）阻害、血圧上昇抑制、又は血圧降下に用いられる組成物、及びその製造方法の提供。【解決手段】アルギニルグルタミン、グルタミニルアルギニン、アルギニルアスパラギン、アスパラギニルアルギニン、及びこれらの塩から選ばれた１種以上のジペプチド化合物の含有量が０．１０ｍｇ／Ｌ以上である、ＡＣＥ阻害用、血圧上昇抑制用、又は血圧降下用の組成物。ユーグレナ細胞から脂質を除去され前記細胞由来の水溶性成分を含んで前記ジペプチド化合物を含有する、ＡＣＥ阻害用、血圧上昇抑制用、又は血圧降下用の組成物。グルタミン酸の含有量が３．４ｍｍｏｌ／Ｌ以上かつアンモニア態窒素の含有量が１３ｍｍｏｌ／Ｌ以上である培地で生育して乾燥させられたユーグレナ細胞、又はその破砕処理物、もしくは前記水溶性成分を含む、ＡＣＥ阻害用、血圧上昇抑制用、又は血圧降下用の組成物。【選択図】図７</description><language>eng ; jpn</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; FOODS OR FOODSTUFFS ; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT ; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES ; VINEGAR ; WINE</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20191010&DB=EPODOC&CC=JP&NR=2019172674A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20191010&DB=EPODOC&CC=JP&NR=2019172674A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>NAKANO OSAHISA</creatorcontrib><creatorcontrib>KUBO NOBUKO</creatorcontrib><creatorcontrib>YOSHIDA KYOKO</creatorcontrib><creatorcontrib>MUTSUSHIRO MINORU</creatorcontrib><creatorcontrib>OZAKI NORIYA</creatorcontrib><title>COMPOSITIONS USED FOR ACE INHIBITION, SUPPRESSION OF BLOOD PRESSURE ELEVATION, OR BLOOD PRESSURE DECREASE, AND METHODS FOR PRODUCING THE SAME</title><description>To provide compositions used for angiotensin I converting enzyme (ACE) inhibition, suppression of blood pressure elevation, or blood pressure decrease, and to provide methods for producing the same.SOLUTION: Provided is a composition for ACE inhibition, suppression of blood pressure elevation, or blood pressure decrease, in which the content of one or more dipeptide compounds selected from arginyl glutamine, glutaminyl arginine, arginyl asparagine, asparaginyl arginine, and salts thereof is 0.10 mg/L or more. The composition for ACE inhibition, suppression of blood pressure elevation, or blood pressure decrease contains a water-soluble component derived from the Euglena cells in which lipid is removed and the dipeptide compound. The composition for ACE inhibition, suppression of blood pressure elevation, or blood pressure decrease contains Euglena cells grown in a medium having a glutamic acid content of 3.4 mmol/L or more and an ammonia nitrogen content of 13 mmol/L or more and dried, or a disrupted product thereof, or the water-soluble component.SELECTED DRAWING: Figure 7
【課題】アンジオテンシンI変換酵素（ＡＣＥ）阻害、血圧上昇抑制、又は血圧降下に用いられる組成物、及びその製造方法の提供。【解決手段】アルギニルグルタミン、グルタミニルアルギニン、アルギニルアスパラギン、アスパラギニルアルギニン、及びこれらの塩から選ばれた１種以上のジペプチド化合物の含有量が０．１０ｍｇ／Ｌ以上である、ＡＣＥ阻害用、血圧上昇抑制用、又は血圧降下用の組成物。ユーグレナ細胞から脂質を除去され前記細胞由来の水溶性成分を含んで前記ジペプチド化合物を含有する、ＡＣＥ阻害用、血圧上昇抑制用、又は血圧降下用の組成物。グルタミン酸の含有量が３．４ｍｍｏｌ／Ｌ以上かつアンモニア態窒素の含有量が１３ｍｍｏｌ／Ｌ以上である培地で生育して乾燥させられたユーグレナ細胞、又はその破砕処理物、もしくは前記水溶性成分を含む、ＡＣＥ阻害用、血圧上昇抑制用、又は血圧降下用の組成物。【選択図】図７</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>FOODS OR FOODSTUFFS</subject><subject>FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT</subject><subject>THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2019</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjTELwjAUhLs4iPofHs4VbBWLY5q8mojNC3mtaykSJ9FC_Rv-Z0t1cnI67r47bhq9JJWO2FSGLEPNqKAgD0IiGKtNPoIYuHbOI_NggArIT0QKxqT2CHjCs_gUh-0PVCg9CsYYhFVQYqVJ8XjiPKlaGnuASiOwKHEeTa7trQ-Lr86iZYGV1KvQPZrQd-0l3MOzObp0neyTLN1lW7H5q_QGHPNAJQ</recordid><startdate>20191010</startdate><enddate>20191010</enddate><creator>NAKANO OSAHISA</creator><creator>KUBO NOBUKO</creator><creator>YOSHIDA KYOKO</creator><creator>MUTSUSHIRO MINORU</creator><creator>OZAKI NORIYA</creator><scope>EVB</scope></search><sort><creationdate>20191010</creationdate><title>COMPOSITIONS USED FOR ACE INHIBITION, SUPPRESSION OF BLOOD PRESSURE ELEVATION, OR BLOOD PRESSURE DECREASE, AND METHODS FOR PRODUCING THE SAME</title><author>NAKANO OSAHISA ; KUBO NOBUKO ; YOSHIDA KYOKO ; MUTSUSHIRO MINORU ; OZAKI NORIYA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_JP2019172674A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; jpn</language><creationdate>2019</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>FOODS OR FOODSTUFFS</topic><topic>FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT</topic><topic>THEIR TREATMENT, NOT COVERED BY OTHER CLASSES</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>NAKANO OSAHISA</creatorcontrib><creatorcontrib>KUBO NOBUKO</creatorcontrib><creatorcontrib>YOSHIDA KYOKO</creatorcontrib><creatorcontrib>MUTSUSHIRO MINORU</creatorcontrib><creatorcontrib>OZAKI NORIYA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>NAKANO OSAHISA</au><au>KUBO NOBUKO</au><au>YOSHIDA KYOKO</au><au>MUTSUSHIRO MINORU</au><au>OZAKI NORIYA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>COMPOSITIONS USED FOR ACE INHIBITION, SUPPRESSION OF BLOOD PRESSURE ELEVATION, OR BLOOD PRESSURE DECREASE, AND METHODS FOR PRODUCING THE SAME</title><date>2019-10-10</date><risdate>2019</risdate><abstract>To provide compositions used for angiotensin I converting enzyme (ACE) inhibition, suppression of blood pressure elevation, or blood pressure decrease, and to provide methods for producing the same.SOLUTION: Provided is a composition for ACE inhibition, suppression of blood pressure elevation, or blood pressure decrease, in which the content of one or more dipeptide compounds selected from arginyl glutamine, glutaminyl arginine, arginyl asparagine, asparaginyl arginine, and salts thereof is 0.10 mg/L or more. The composition for ACE inhibition, suppression of blood pressure elevation, or blood pressure decrease contains a water-soluble component derived from the Euglena cells in which lipid is removed and the dipeptide compound. The composition for ACE inhibition, suppression of blood pressure elevation, or blood pressure decrease contains Euglena cells grown in a medium having a glutamic acid content of 3.4 mmol/L or more and an ammonia nitrogen content of 13 mmol/L or more and dried, or a disrupted product thereof, or the water-soluble component.SELECTED DRAWING: Figure 7
【課題】アンジオテンシンI変換酵素（ＡＣＥ）阻害、血圧上昇抑制、又は血圧降下に用いられる組成物、及びその製造方法の提供。【解決手段】アルギニルグルタミン、グルタミニルアルギニン、アルギニルアスパラギン、アスパラギニルアルギニン、及びこれらの塩から選ばれた１種以上のジペプチド化合物の含有量が０．１０ｍｇ／Ｌ以上である、ＡＣＥ阻害用、血圧上昇抑制用、又は血圧降下用の組成物。ユーグレナ細胞から脂質を除去され前記細胞由来の水溶性成分を含んで前記ジペプチド化合物を含有する、ＡＣＥ阻害用、血圧上昇抑制用、又は血圧降下用の組成物。グルタミン酸の含有量が３．４ｍｍｏｌ／Ｌ以上かつアンモニア態窒素の含有量が１３ｍｍｏｌ／Ｌ以上である培地で生育して乾燥させられたユーグレナ細胞、又はその破砕処理物、もしくは前記水溶性成分を含む、ＡＣＥ阻害用、血圧上昇抑制用、又は血圧降下用の組成物。【選択図】図７</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; jpn |
| recordid | cdi_epo_espacenet_JP2019172674A |
| source | esp@cenet |
| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES VINEGAR WINE |
| title | COMPOSITIONS USED FOR ACE INHIBITION, SUPPRESSION OF BLOOD PRESSURE ELEVATION, OR BLOOD PRESSURE DECREASE, AND METHODS FOR PRODUCING THE SAME |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-05T09%3A39%3A46IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=NAKANO%20OSAHISA&rft.date=2019-10-10&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EJP2019172674A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |