METHODS, REAGENTS AND KITS FOR FLOW CYTOMETRIC IMMUNOPHENOTYPING TEST

PROBLEM TO BE SOLVED: To provide improved and well-defined antibody panels that avoid misinterpretation and over-interpretation of result.SOLUTION: The invention relates to a field of flow cytometry, and more particularly to a panel of antibody reagents conjugated to fluorescent compounds. Provided...

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Hauptverfasser: VINCENT HENDRICUS JOHANNES VAN DER VELDEN, CARLOS EDUARDO PEDREIRA, VAHID ASNAFI, MARTA MARIN AYUSO, JACOBUS JOHANNES MARIA VAN DONGEN, SEBASTIAN BOETTCHER, PAULO JORGE MONTEIRO DA SILVA LUCIO, JOSE ALBERTO ORFAO DE MATOS CORREIA E VALE, LUDOVIC BERNARD SIMON LHERMITTE, JUAN ALEJANDRO FLORES-MONTERO, ANDREW CRAIG RAWSTRON, ESTER MEJSTRIKOVA, RUTH MARY DE TUTE, TOMASZ SZCZEPANSKI, JULIA MARIA ALMEIDA PARRA
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creator VINCENT HENDRICUS JOHANNES VAN DER VELDEN
CARLOS EDUARDO PEDREIRA
VAHID ASNAFI
MARTA MARIN AYUSO
JACOBUS JOHANNES MARIA VAN DONGEN
SEBASTIAN BOETTCHER
PAULO JORGE MONTEIRO DA SILVA LUCIO
JOSE ALBERTO ORFAO DE MATOS CORREIA E VALE
LUDOVIC BERNARD SIMON LHERMITTE
JUAN ALEJANDRO FLORES-MONTERO
ANDREW CRAIG RAWSTRON
ESTER MEJSTRIKOVA
RUTH MARY DE TUTE
TOMASZ SZCZEPANSKI
JULIA MARIA ALMEIDA PARRA
description PROBLEM TO BE SOLVED: To provide improved and well-defined antibody panels that avoid misinterpretation and over-interpretation of result.SOLUTION: The invention relates to a field of flow cytometry, and more particularly to a panel of antibody reagents conjugated to fluorescent compounds. Provided are reagent compositions, comprising at least eight distinct fluorochrome-conjugated antibodies comprising a set of at least three identification antibodies for identification of a leukocyte population of a target and at least four characterization antibodies for further characterization and/or classification of the leukocyte population. Also provided are kits and methods related to the reagent compositions.SELECTED DRAWING: Figure 1 【課題】1つには、結果の誤った解釈および過大な解釈を回避する、改善され、明確に定義された抗体パネルを提供すること。【解決手段】本発明は、フローサイトメトリーの分野、より具体的には、蛍光化合物にコンジュゲートさせた抗体試薬のパネルに関する。目的の白血球集団を同定するための少なくとも3つの同定用抗体と、前記白血球集団をさらに特徴付けおよび/または分類するための少なくとも4つの特徴付け用抗体とのセットを含む、少なくとも8つの明確に異なる蛍光色素コンジュゲート化抗体を含む試薬組成物を提供する。また、試薬組成物に関連があるキットおよび方法も提供する。【選択図】図1
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subjects INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
title METHODS, REAGENTS AND KITS FOR FLOW CYTOMETRIC IMMUNOPHENOTYPING TEST
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