TRANSDERMAL PATCH FOR ADMINISTERING FENTANYL
PROBLEM TO BE SOLVED: To provide a method for transdermal administration of fentanyl and an analog thereof for analgesia, and a patch therefor.SOLUTION: The present invention relates to a transdermal patch for administering fentanyl or an analog thereof through the skin comprising: a backing layer;...
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| creator | LI SHAOLING STEPIC JANE OSDOL WILLIAM W VAN VENKATRAMAN SUBRAMANIAN S GALE ROBERT M |
| description | PROBLEM TO BE SOLVED: To provide a method for transdermal administration of fentanyl and an analog thereof for analgesia, and a patch therefor.SOLUTION: The present invention relates to a transdermal patch for administering fentanyl or an analog thereof through the skin comprising: a backing layer; and a reservoir disposed on the backing layer, wherein the reservoir has a thickness of about 0.0125-0.1 mm, at least the skin contacting surface of the reservoir is adhesive, and the reservoir comprises a single phase polymeric composition free of undissolved components containing an amount of fentanyl or an analog thereof sufficient to induce and maintain analgesia in a human for at least three days. And the patch is a rate controlling-free monolithic transdermal patch, wherein fentanyl of a base form is present in the amount of about 7-12% by weight.SELECTED DRAWING: None
【課題】痛覚消失目的のためのフェンタニル及びその類似体の経皮的投与の方法およびそのための張り付け剤の提供。【解決手段】裏打ち層、および裏打ち層上に配置された貯蔵体であって、約０．０１２５〜０．１ｍｍの厚さを有し、前記貯蔵体の少なくとも皮膚接触面が接着性であり、前記貯蔵体が、少なくとも３日間ヒトにおける痛覚消失を誘発し、維持するのに十分量のフェンタニルまたはその類似体を含有する、比溶解成分を含まない単層ポリマー組成物を含有する、貯蔵体を含んでなり、且つ、非速度制御型モノリスの経皮膚的張り付け剤であり、塩基形態のフェンタニルが約７〜１２重量％の量で存在する、皮膚をとおしてフェンタニルまたはその類似体を投与するための経皮的貼り付け剤。【選択図】なし |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_JP2017014268A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>JP2017014268A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_JP2017014268A3</originalsourceid><addsrcrecordid>eNrjZNAJCXL0C3ZxDfJ19FEIcAxx9lBw8w9ScHTx9fTzDA5xDfL0c1dwc_ULcfSL9OFhYE1LzClO5YXS3AxKbq5ALbqpBfnxqcUFicmpeakl8V4BRgaG5gaGJkZmFo7GRCkCAPLvJcg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>TRANSDERMAL PATCH FOR ADMINISTERING FENTANYL</title><source>esp@cenet</source><creator>LI SHAOLING ; STEPIC JANE ; OSDOL WILLIAM W VAN ; VENKATRAMAN SUBRAMANIAN S ; GALE ROBERT M</creator><creatorcontrib>LI SHAOLING ; STEPIC JANE ; OSDOL WILLIAM W VAN ; VENKATRAMAN SUBRAMANIAN S ; GALE ROBERT M</creatorcontrib><description>PROBLEM TO BE SOLVED: To provide a method for transdermal administration of fentanyl and an analog thereof for analgesia, and a patch therefor.SOLUTION: The present invention relates to a transdermal patch for administering fentanyl or an analog thereof through the skin comprising: a backing layer; and a reservoir disposed on the backing layer, wherein the reservoir has a thickness of about 0.0125-0.1 mm, at least the skin contacting surface of the reservoir is adhesive, and the reservoir comprises a single phase polymeric composition free of undissolved components containing an amount of fentanyl or an analog thereof sufficient to induce and maintain analgesia in a human for at least three days. And the patch is a rate controlling-free monolithic transdermal patch, wherein fentanyl of a base form is present in the amount of about 7-12% by weight.SELECTED DRAWING: None
【課題】痛覚消失目的のためのフェンタニル及びその類似体の経皮的投与の方法およびそのための張り付け剤の提供。【解決手段】裏打ち層、および裏打ち層上に配置された貯蔵体であって、約０．０１２５〜０．１ｍｍの厚さを有し、前記貯蔵体の少なくとも皮膚接触面が接着性であり、前記貯蔵体が、少なくとも３日間ヒトにおける痛覚消失を誘発し、維持するのに十分量のフェンタニルまたはその類似体を含有する、比溶解成分を含まない単層ポリマー組成物を含有する、貯蔵体を含んでなり、且つ、非速度制御型モノリスの経皮膚的張り付け剤であり、塩基形態のフェンタニルが約７〜１２重量％の量で存在する、皮膚をとおしてフェンタニルまたはその類似体を投与するための経皮的貼り付け剤。【選択図】なし</description><language>eng ; jpn</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2017</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170119&DB=EPODOC&CC=JP&NR=2017014268A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170119&DB=EPODOC&CC=JP&NR=2017014268A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LI SHAOLING</creatorcontrib><creatorcontrib>STEPIC JANE</creatorcontrib><creatorcontrib>OSDOL WILLIAM W VAN</creatorcontrib><creatorcontrib>VENKATRAMAN SUBRAMANIAN S</creatorcontrib><creatorcontrib>GALE ROBERT M</creatorcontrib><title>TRANSDERMAL PATCH FOR ADMINISTERING FENTANYL</title><description>PROBLEM TO BE SOLVED: To provide a method for transdermal administration of fentanyl and an analog thereof for analgesia, and a patch therefor.SOLUTION: The present invention relates to a transdermal patch for administering fentanyl or an analog thereof through the skin comprising: a backing layer; and a reservoir disposed on the backing layer, wherein the reservoir has a thickness of about 0.0125-0.1 mm, at least the skin contacting surface of the reservoir is adhesive, and the reservoir comprises a single phase polymeric composition free of undissolved components containing an amount of fentanyl or an analog thereof sufficient to induce and maintain analgesia in a human for at least three days. And the patch is a rate controlling-free monolithic transdermal patch, wherein fentanyl of a base form is present in the amount of about 7-12% by weight.SELECTED DRAWING: None
【課題】痛覚消失目的のためのフェンタニル及びその類似体の経皮的投与の方法およびそのための張り付け剤の提供。【解決手段】裏打ち層、および裏打ち層上に配置された貯蔵体であって、約０．０１２５〜０．１ｍｍの厚さを有し、前記貯蔵体の少なくとも皮膚接触面が接着性であり、前記貯蔵体が、少なくとも３日間ヒトにおける痛覚消失を誘発し、維持するのに十分量のフェンタニルまたはその類似体を含有する、比溶解成分を含まない単層ポリマー組成物を含有する、貯蔵体を含んでなり、且つ、非速度制御型モノリスの経皮膚的張り付け剤であり、塩基形態のフェンタニルが約７〜１２重量％の量で存在する、皮膚をとおしてフェンタニルまたはその類似体を投与するための経皮的貼り付け剤。【選択図】なし</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2017</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNAJCXL0C3ZxDfJ19FEIcAxx9lBw8w9ScHTx9fTzDA5xDfL0c1dwc_ULcfSL9OFhYE1LzClO5YXS3AxKbq5ALbqpBfnxqcUFicmpeakl8V4BRgaG5gaGJkZmFo7GRCkCAPLvJcg</recordid><startdate>20170119</startdate><enddate>20170119</enddate><creator>LI SHAOLING</creator><creator>STEPIC JANE</creator><creator>OSDOL WILLIAM W VAN</creator><creator>VENKATRAMAN SUBRAMANIAN S</creator><creator>GALE ROBERT M</creator><scope>EVB</scope></search><sort><creationdate>20170119</creationdate><title>TRANSDERMAL PATCH FOR ADMINISTERING FENTANYL</title><author>LI SHAOLING ; STEPIC JANE ; OSDOL WILLIAM W VAN ; VENKATRAMAN SUBRAMANIAN S ; GALE ROBERT M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_JP2017014268A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; jpn</language><creationdate>2017</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>LI SHAOLING</creatorcontrib><creatorcontrib>STEPIC JANE</creatorcontrib><creatorcontrib>OSDOL WILLIAM W VAN</creatorcontrib><creatorcontrib>VENKATRAMAN SUBRAMANIAN S</creatorcontrib><creatorcontrib>GALE ROBERT M</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LI SHAOLING</au><au>STEPIC JANE</au><au>OSDOL WILLIAM W VAN</au><au>VENKATRAMAN SUBRAMANIAN S</au><au>GALE ROBERT M</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>TRANSDERMAL PATCH FOR ADMINISTERING FENTANYL</title><date>2017-01-19</date><risdate>2017</risdate><abstract>PROBLEM TO BE SOLVED: To provide a method for transdermal administration of fentanyl and an analog thereof for analgesia, and a patch therefor.SOLUTION: The present invention relates to a transdermal patch for administering fentanyl or an analog thereof through the skin comprising: a backing layer; and a reservoir disposed on the backing layer, wherein the reservoir has a thickness of about 0.0125-0.1 mm, at least the skin contacting surface of the reservoir is adhesive, and the reservoir comprises a single phase polymeric composition free of undissolved components containing an amount of fentanyl or an analog thereof sufficient to induce and maintain analgesia in a human for at least three days. And the patch is a rate controlling-free monolithic transdermal patch, wherein fentanyl of a base form is present in the amount of about 7-12% by weight.SELECTED DRAWING: None
【課題】痛覚消失目的のためのフェンタニル及びその類似体の経皮的投与の方法およびそのための張り付け剤の提供。【解決手段】裏打ち層、および裏打ち層上に配置された貯蔵体であって、約０．０１２５〜０．１ｍｍの厚さを有し、前記貯蔵体の少なくとも皮膚接触面が接着性であり、前記貯蔵体が、少なくとも３日間ヒトにおける痛覚消失を誘発し、維持するのに十分量のフェンタニルまたはその類似体を含有する、比溶解成分を含まない単層ポリマー組成物を含有する、貯蔵体を含んでなり、且つ、非速度制御型モノリスの経皮膚的張り付け剤であり、塩基形態のフェンタニルが約７〜１２重量％の量で存在する、皮膚をとおしてフェンタニルまたはその類似体を投与するための経皮的貼り付け剤。【選択図】なし</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | TRANSDERMAL PATCH FOR ADMINISTERING FENTANYL |
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