NEW UREIDE CARBONYL OCTAHYDROQUINOLINE DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AND APPLICATION THEREOF

PROBLEM TO BE SOLVED: To provide a compound having D2 dopamine receptor agonistic effect and less 5-HTreceptor stimulation effect, which is useful for treatment and prevention of Parkinson disease, restless legs syndrome or hyperprolactinemia.SOLUTION: There is provided an ureide carbonyl octahydroq...

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Bibliographische Detailangaben
Hauptverfasser: NISHIMURA TOSHIHIRO, KAMBE HIROKI
Format: Patent
Sprache:eng ; jpn
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a compound having D2 dopamine receptor agonistic effect and less 5-HTreceptor stimulation effect, which is useful for treatment and prevention of Parkinson disease, restless legs syndrome or hyperprolactinemia.SOLUTION: There is provided an ureide carbonyl octahydroquinoline derivative represented, for example, by 2, 3 or the like in the following table.SELECTED DRAWING: None 【課題】パーキンソン病、レストレスレッグス症候群又は高プロラクチン血症の治療または予防に有効な、ドパミンD2受容体アゴニスト作用を有し、5−HT2B受容体刺激作用の少ない化合物の提供。【解決手段】例えば下記表中の2,3等で表される、ウレイドカルボニルオクタヒドロキノリン誘導体。【選択図】なし