SUBSTANCE-DELIVERING CARRIER FOR PRODUCTIVE CELLS OF FUCOSYLATED SUGAR CHAIN
PROBLEM TO BE SOLVED: To provide a carrier for delivering a substance, for treating tumor diseases, specifically to productive cells of fucosylated sugar chain.SOLUTION: Provided is a carrier for delivering a substance to productive cells of fucosylated sugar chain comprising a fucose. The carrier i...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; jpn |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | KATO JUNJI TAKIMOTO OSAMU |
| description | PROBLEM TO BE SOLVED: To provide a carrier for delivering a substance, for treating tumor diseases, specifically to productive cells of fucosylated sugar chain.SOLUTION: Provided is a carrier for delivering a substance to productive cells of fucosylated sugar chain comprising a fucose. The carrier is selected from the group consisting of tumor cells in which a production amount of a fucosylated sugar chain in fucosylated sugar chain-producing cells is two times or more than that in a normal cells, and tumor cells in which the concentration of CA 19-9, Span-1, or Dupan-2 in the supernatant obtained by culturing 5×10cells in a culture medium of 3 ml for 48 hours becomes 150 U/ml or more, 94 U/ml or more, or 80 U/ml or more respectively.
【課題】腫瘍性疾患を処置するための、フコシル化糖鎖産生細胞特異的に物質を送達する担体の提供。【解決手段】フコースを含む、フコシル化糖鎖産生細胞に物質を送達するための担体であって、フコシル化糖鎖産生細胞が、フコシル化糖鎖産生量が正常細胞に比べ２倍以上である腫瘍細胞、及び５?１０６個の細胞を３ｍｌの培地中で４８時間培養した上清中のＣＡ１９−９、Ｓｐａｎ−１またはＤｕｐａｎ−２の濃度が、それぞれ、１５０Ｕ／ｍｌ以上、９４Ｕ／ｍｌ以上または８０Ｕ／ｍｌ以上となる腫瘍細胞、からなる群から選択される、前記担体。【選択図】なし |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_JP2015017112A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>JP2015017112A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_JP2015017112A3</originalsourceid><addsrcrecordid>eNqNyrEKwjAQgOEsDqK-w-FeaCriHC-XNhKSckkKTqVInEQL9f3RwQdw-ofvXwsX8zkm5ZEqTc4OxNa3gIrZEoMJDD0HnTF9CZCcixAMmIwhXp1KpCHmVjFgp6zfitV9eixl9-tG7A0l7Koyv8ayzNOtPMt7vPRNLY-1PEnZqMNf0wctwC5x</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>SUBSTANCE-DELIVERING CARRIER FOR PRODUCTIVE CELLS OF FUCOSYLATED SUGAR CHAIN</title><source>esp@cenet</source><creator>KATO JUNJI ; TAKIMOTO OSAMU</creator><creatorcontrib>KATO JUNJI ; TAKIMOTO OSAMU</creatorcontrib><description>PROBLEM TO BE SOLVED: To provide a carrier for delivering a substance, for treating tumor diseases, specifically to productive cells of fucosylated sugar chain.SOLUTION: Provided is a carrier for delivering a substance to productive cells of fucosylated sugar chain comprising a fucose. The carrier is selected from the group consisting of tumor cells in which a production amount of a fucosylated sugar chain in fucosylated sugar chain-producing cells is two times or more than that in a normal cells, and tumor cells in which the concentration of CA 19-9, Span-1, or Dupan-2 in the supernatant obtained by culturing 5×10cells in a culture medium of 3 ml for 48 hours becomes 150 U/ml or more, 94 U/ml or more, or 80 U/ml or more respectively.
【課題】腫瘍性疾患を処置するための、フコシル化糖鎖産生細胞特異的に物質を送達する担体の提供。【解決手段】フコースを含む、フコシル化糖鎖産生細胞に物質を送達するための担体であって、フコシル化糖鎖産生細胞が、フコシル化糖鎖産生量が正常細胞に比べ２倍以上である腫瘍細胞、及び５?１０６個の細胞を３ｍｌの培地中で４８時間培養した上清中のＣＡ１９−９、Ｓｐａｎ−１またはＤｕｐａｎ−２の濃度が、それぞれ、１５０Ｕ／ｍｌ以上、９４Ｕ／ｍｌ以上または８０Ｕ／ｍｌ以上となる腫瘍細胞、からなる群から選択される、前記担体。【選択図】なし</description><language>eng ; jpn</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150129&DB=EPODOC&CC=JP&NR=2015017112A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150129&DB=EPODOC&CC=JP&NR=2015017112A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KATO JUNJI</creatorcontrib><creatorcontrib>TAKIMOTO OSAMU</creatorcontrib><title>SUBSTANCE-DELIVERING CARRIER FOR PRODUCTIVE CELLS OF FUCOSYLATED SUGAR CHAIN</title><description>PROBLEM TO BE SOLVED: To provide a carrier for delivering a substance, for treating tumor diseases, specifically to productive cells of fucosylated sugar chain.SOLUTION: Provided is a carrier for delivering a substance to productive cells of fucosylated sugar chain comprising a fucose. The carrier is selected from the group consisting of tumor cells in which a production amount of a fucosylated sugar chain in fucosylated sugar chain-producing cells is two times or more than that in a normal cells, and tumor cells in which the concentration of CA 19-9, Span-1, or Dupan-2 in the supernatant obtained by culturing 5×10cells in a culture medium of 3 ml for 48 hours becomes 150 U/ml or more, 94 U/ml or more, or 80 U/ml or more respectively.
【課題】腫瘍性疾患を処置するための、フコシル化糖鎖産生細胞特異的に物質を送達する担体の提供。【解決手段】フコースを含む、フコシル化糖鎖産生細胞に物質を送達するための担体であって、フコシル化糖鎖産生細胞が、フコシル化糖鎖産生量が正常細胞に比べ２倍以上である腫瘍細胞、及び５?１０６個の細胞を３ｍｌの培地中で４８時間培養した上清中のＣＡ１９−９、Ｓｐａｎ−１またはＤｕｐａｎ−２の濃度が、それぞれ、１５０Ｕ／ｍｌ以上、９４Ｕ／ｍｌ以上または８０Ｕ／ｍｌ以上となる腫瘍細胞、からなる群から選択される、前記担体。【選択図】なし</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2015</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyrEKwjAQgOEsDqK-w-FeaCriHC-XNhKSckkKTqVInEQL9f3RwQdw-ofvXwsX8zkm5ZEqTc4OxNa3gIrZEoMJDD0HnTF9CZCcixAMmIwhXp1KpCHmVjFgp6zfitV9eixl9-tG7A0l7Koyv8ayzNOtPMt7vPRNLY-1PEnZqMNf0wctwC5x</recordid><startdate>20150129</startdate><enddate>20150129</enddate><creator>KATO JUNJI</creator><creator>TAKIMOTO OSAMU</creator><scope>EVB</scope></search><sort><creationdate>20150129</creationdate><title>SUBSTANCE-DELIVERING CARRIER FOR PRODUCTIVE CELLS OF FUCOSYLATED SUGAR CHAIN</title><author>KATO JUNJI ; TAKIMOTO OSAMU</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_JP2015017112A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; jpn</language><creationdate>2015</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>KATO JUNJI</creatorcontrib><creatorcontrib>TAKIMOTO OSAMU</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KATO JUNJI</au><au>TAKIMOTO OSAMU</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SUBSTANCE-DELIVERING CARRIER FOR PRODUCTIVE CELLS OF FUCOSYLATED SUGAR CHAIN</title><date>2015-01-29</date><risdate>2015</risdate><abstract>PROBLEM TO BE SOLVED: To provide a carrier for delivering a substance, for treating tumor diseases, specifically to productive cells of fucosylated sugar chain.SOLUTION: Provided is a carrier for delivering a substance to productive cells of fucosylated sugar chain comprising a fucose. The carrier is selected from the group consisting of tumor cells in which a production amount of a fucosylated sugar chain in fucosylated sugar chain-producing cells is two times or more than that in a normal cells, and tumor cells in which the concentration of CA 19-9, Span-1, or Dupan-2 in the supernatant obtained by culturing 5×10cells in a culture medium of 3 ml for 48 hours becomes 150 U/ml or more, 94 U/ml or more, or 80 U/ml or more respectively.
【課題】腫瘍性疾患を処置するための、フコシル化糖鎖産生細胞特異的に物質を送達する担体の提供。【解決手段】フコースを含む、フコシル化糖鎖産生細胞に物質を送達するための担体であって、フコシル化糖鎖産生細胞が、フコシル化糖鎖産生量が正常細胞に比べ２倍以上である腫瘍細胞、及び５?１０６個の細胞を３ｍｌの培地中で４８時間培養した上清中のＣＡ１９−９、Ｓｐａｎ−１またはＤｕｐａｎ−２の濃度が、それぞれ、１５０Ｕ／ｍｌ以上、９４Ｕ／ｍｌ以上または８０Ｕ／ｍｌ以上となる腫瘍細胞、からなる群から選択される、前記担体。【選択図】なし</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; jpn |
| recordid | cdi_epo_espacenet_JP2015017112A |
| source | esp@cenet |
| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | SUBSTANCE-DELIVERING CARRIER FOR PRODUCTIVE CELLS OF FUCOSYLATED SUGAR CHAIN |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-17T17%3A20%3A11IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=KATO%20JUNJI&rft.date=2015-01-29&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EJP2015017112A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |