METHOD FOR DETECTING AGGREGATE-FORMING CIRCULATING PROTEIN FORMS BY USING AGENT FOR FLOCCULATING THE FORMS AND AGENT FOR CAPTURING FORMED AGGREGATES

PROBLEM TO BE SOLVED: To provide a method for detecting aggregate-forming circulating protein forms with the use of an agent for flocculating the forms and an agent for capturing the formed aggregates.SOLUTION: The invention concerns a method for detecting aggregate-forming circulating protein forms...

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Bibliographische Detailangaben
Hauptverfasser: SEBASTIEN CECILLON, ANTHONY WILLIAM COLEMAN, ANNE EVENO-NOBILE, MARC RODRIGUE, HERVE PERRON
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:PROBLEM TO BE SOLVED: To provide a method for detecting aggregate-forming circulating protein forms with the use of an agent for flocculating the forms and an agent for capturing the formed aggregates.SOLUTION: The invention concerns a method for detecting aggregate-forming circulating protein forms in a biological specimen of human origin which may contain the aggregate-forming circulating protein forms. The method uses a non-protein agent I for causing aggregation of circulating forms of non-infectious proteins which is involved in a pathological aggregation process of a central nervous system, and/or a non-protein agent II for capturing natural aggregates of the aggregate-forming circulating protein forms or aggregates derived by the agent I.