PROCESSES FOR PREPARING 3-BENZAZEPINES

PROBLEM TO BE SOLVED: To provide processes and intermediates for the preparation of 3-benzazepines and salts thereof which can be useful as serotonin (5-HT) receptor agonists for the treatment of, for example, central nervous system disorders such as obesity.SOLUTION: Serotonin (5-HT) neurotransmiss...

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Hauptverfasser: REY MAX, SMITH BRIAN, GILSON CHARLES A III, WEIGL ULRICH, ESTRADA SCOTT A, SENGUPTA DIPANJAN, BURBAUM BEVERLY W, AYTES SHELLEY
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide processes and intermediates for the preparation of 3-benzazepines and salts thereof which can be useful as serotonin (5-HT) receptor agonists for the treatment of, for example, central nervous system disorders such as obesity.SOLUTION: Serotonin (5-HT) neurotransmission plays an important role in numerous physiological processes both in health disorders and in psychiatric disorders. For example, 5-HT has been implicated in the regulation of feeding behavior. 5-HT is believed to work by inducing a feeling of fullness, and thereby eating stops and fewer calories are taken.