METHOD OF MANUFACTURING GRANULES OR TABLETS FORMED AFTER PELLETIZING MULBERRY TWIGS, MULBERRY LEAVES AND RED-SEPALED EVENING PRIMROSE BY IONIZED DEXTRIN, AND BIOACTIVITY

PROBLEM TO BE SOLVED: To provide ideal functional food by which a longer life-span and the elongating effect of a healthy life-span are expected.SOLUTION: As a result of manufacturing mulberry leaf fine powder, mulberry twig fine powder and red-sepaled evening primrose (Oenothera erythrosepala) fine powder under thorough quality control, and formulating them by ionized dextrin, an effect of suppressing an increase of blood sugar level after loading glucose exhibited the same effect as a target drug (Basen), and usefulness as diabetes prevention and diabetes therapeutic agent was recognized. -sitosterol glycoside selectively contained in red-sepaled evening primrose, and furthermore, 1-deoxynojirimycin contained only in mulberry and polyphenols being flavonoid-based polyphenol such as resveratrol and quercetin and phenol-based polyphenol such as chlorogenic acid, vitamin B1 which is essential in metabolizing glucide and lipid exhibit complex and synergistic preventive effects to vascular diseases derived from lifestyle-related diseases such as hypertension including diabetes.