ORAL SOLID COMPOSITION REDUCED IN IRRITATION TO DIGESTIVE TRACT

PROBLEM TO BE SOLVED: To provide a solid composition that prevents irritation to digestive tracts by a drug having irritation properties to digestive tracts and can be produced by a simple production method.SOLUTION: The oral solid composition contains a digestive tract irritating drug and a water-s...

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Hauptverfasser: KONUKI YOICHI, CHIBA AKIRA, ISHIKAWA MASAGO, OKADA MINORU, KANBE HIDEYOSHI, MIYADAI NOBUO
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creator KONUKI YOICHI
CHIBA AKIRA
ISHIKAWA MASAGO
OKADA MINORU
KANBE HIDEYOSHI
MIYADAI NOBUO
description PROBLEM TO BE SOLVED: To provide a solid composition that prevents irritation to digestive tracts by a drug having irritation properties to digestive tracts and can be produced by a simple production method.SOLUTION: The oral solid composition contains a digestive tract irritating drug and a water-swellable polymer, and can be obtained by performing wet granulation with water and hydrous alcohol.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title ORAL SOLID COMPOSITION REDUCED IN IRRITATION TO DIGESTIVE TRACT
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