METHOD FOR PRODUCING CANDESARTAN CILEXETIL-CONTAINING GRANULE AND METHOD FOR PRODUCING CANDESARTAN CILEXETIL-CONTAINING TABLET

METHOD FOR PRODUCING CANDESARTAN CILEXETIL-CONTAINING GRANULE AND METHOD FOR PRODUCING CANDESARTAN CILEXETIL-CONTAINING TABLET

PROBLEM TO BE SOLVED: To provide a method for producing candesartan cilexetil-containing granules wherein candesartan cilexetil is prevented from decomposing and stabilized, and a method for producing a candesartan cilexetil-containing tablet wherein candesartan cilexetil is prevented from decomposi...

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Hauptverfasser: UETSUKI KENJI, FUKUHARA YASUSHI, NAKAGAWA TOMOYA, HIZAKI MASAYA
Format: Patent
Sprache:eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator UETSUKI KENJI
FUKUHARA YASUSHI
NAKAGAWA TOMOYA
HIZAKI MASAYA
description PROBLEM TO BE SOLVED: To provide a method for producing candesartan cilexetil-containing granules wherein candesartan cilexetil is prevented from decomposing and stabilized, and a method for producing a candesartan cilexetil-containing tablet wherein candesartan cilexetil is prevented from decomposing and stabilized.SOLUTION: In the method for producing candesartan cilexetil-containing granules, a mixture containing candesartan cilexetil and D-mannitol is granulated in a fluidized bed. Granules obtained by this method, the method for producing a candesartan cilexetil-containing tablet by forming the granules into a tablet, and the candesartan cilexetil-containing tablet obtained by the method are also provided.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title METHOD FOR PRODUCING CANDESARTAN CILEXETIL-CONTAINING GRANULE AND METHOD FOR PRODUCING CANDESARTAN CILEXETIL-CONTAINING TABLET
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