alpha-2-delta LIGAND TO TREAT LOWER URINARY TRACT SYMPTOM

PROBLEM TO BE SOLVED: To provide a compound useful as a medicament for the treatment of LUTS, other than urinary incontinence, associated with OAB and/or BPH. SOLUTION: Use of an α-2-δ ligand, or a pharmaceutically acceptable derivative thereof, for the manufacture of the medicament for the treatmen...

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Hauptverfasser: WESTBROOK SIMON LEMPRIER, TAYLOR CHARLES PRICE JR, THORPE ANDREW JOHN, WUSTROW DAVID JUERGEN
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a compound useful as a medicament for the treatment of LUTS, other than urinary incontinence, associated with OAB and/or BPH. SOLUTION: Use of an α-2-δ ligand, or a pharmaceutically acceptable derivative thereof, for the manufacture of the medicament for the treatment of LUTS, other than urinary incontinence, associated with OAB and/or BPH is provided. Preferred α-2-δ ligands include gabapentin, pregabalin, (1α,3α,5α)(3-amino-methyl-bicyclo[3.2.0]hept-3-yl)-acetic acid, 4-(3-fluoro-benzyl)-pyrrolidine-2-carboxylic acid, etc. COPYRIGHT: (C)2011,JPO&INPIT