THIAZOLIDINEDIONE COMPOUND
PROBLEM TO BE SOLVED: To provide a compound useful as a medicine, in particular as an insulin secretion promoter and a prophylactic and/or therapeutic agent for diseases associated with GPR40 such as diabetes.SOLUTION: The invention is accomplished based on a finding resulting from study on a compou...
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| creator | YOSHIDA SHIGERU NEGORO KENJI ONUKI KEI BEITOKU YASUHIRO KURAMOTO KAZUYUKI KUROSAKI TOSHIO IWASAKI FUMIYOSHI SOGA TAKATOSHI |
| description | PROBLEM TO BE SOLVED: To provide a compound useful as a medicine, in particular as an insulin secretion promoter and a prophylactic and/or therapeutic agent for diseases associated with GPR40 such as diabetes.SOLUTION: The invention is accomplished based on a finding resulting from study on a compound having a GPR40 receptor agonist action, that a thiazolidinedione compound including thiazolidinedione binding to a 6-membered monocyclic aromatic ring via a carbon atom with the aromatic ring further binding to benzene substituted with a 6-membered monocyclic aromatic ring via a linker, and a salt thereof exhibit excellent GPR40 agonist activity. The thiazolidinedione compound can be used as an insulin secretion promoter, and a prophylactic and/or therapeutic agent for diabetes. |
| format | Patent |
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The thiazolidinedione compound can be used as an insulin secretion promoter, and a prophylactic and/or therapeutic agent for diabetes.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | THIAZOLIDINEDIONE COMPOUND |
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