COMPOUND HAVING PHYSIOLOGICAL COOLING EFFECT

PROBLEM TO BE SOLVED: To provide a compound causing physiological cooling effect when applied to the skin or mucosa. SOLUTION: The compound is represented by formula (I), (wherein, R1is menthan-3-yl; R2is ethylene, propylene, trimethylene, tetramethylene or formula (a); X is O, S or NH; Z is O; Y is...

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Hauptverfasser: SURBURG HORST DR, HOPP RUDOLF, PELZER RALF
Format: Patent
Sprache:eng
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a compound causing physiological cooling effect when applied to the skin or mucosa. SOLUTION: The compound is represented by formula (I), (wherein, R1is menthan-3-yl; R2is ethylene, propylene, trimethylene, tetramethylene or formula (a); X is O, S or NH; Z is O; Y is hydroxy, a 1-10C alkoxy, a 2-6C acyloxy or mercapto; m and n are each independently an integer of 1-3; and m+n≤4) or formula (II) except formulas (b). COPYRIGHT: (C)2005,JPO&NCIPI