ACYLSULFONAMIDE DERIVATIVE

PROBLEM TO BE SOLVED: To provide an ACC (acetyl-CoA carboxylase) activity inhibitor effective for treatment of hyperlipemia induced by obesity and fatness, abnormal glucose tolerance, diabetes, diabetic complications, hypertension and arteriosclerosis considered to be based on fatty liver and insuli...

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Hauptverfasser: MAEZONO KATSUMI, KONDO NOBUO, NIHEI YUKIO, SUZUKI NOBUYASU, ICHINOSE HIDEHIRO, YAMAMOTO TAKASHI, NAKANISHI EIJI, HATANAKA TOSHIHIRO, OSUMI KOJI
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creator MAEZONO KATSUMI
KONDO NOBUO
NIHEI YUKIO
SUZUKI NOBUYASU
ICHINOSE HIDEHIRO
YAMAMOTO TAKASHI
NAKANISHI EIJI
HATANAKA TOSHIHIRO
OSUMI KOJI
description PROBLEM TO BE SOLVED: To provide an ACC (acetyl-CoA carboxylase) activity inhibitor effective for treatment of hyperlipemia induced by obesity and fatness, abnormal glucose tolerance, diabetes, diabetic complications, hypertension and arteriosclerosis considered to be based on fatty liver and insulin tolerance. SOLUTION: An acylsulfonamide derivative represented by general formula (1), its analogue or its pharmaceutically acceptable salt has effective inhibitory actions on the ACC activity. COPYRIGHT: (C)2005,JPO&NCIPI
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title ACYLSULFONAMIDE DERIVATIVE
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