NEW 9-N-BICYCLIC NUCLEOSIDE AGENT USEFUL AS SELECTIVE INHIBITOR OF PROINFLAMMATORY CYTOKINE

PROBLEM TO BE SOLVED: To provide selective inhibitors of proinflammatory cytokines. SOLUTION: The inhibitors are provided by using new 9-N-bicyclic nucleoside compound, i.e, a compound of the formula or a pharmaceutically permissible salt thereof. (Wherein, Y is N or CH; Z1and Z2are each H, a haloge...

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Hauptverfasser:	BORCHERDING DAVID R, MUNSON H RANDALL JR, EDWARDS III CARL K
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	PROBLEM TO BE SOLVED: To provide selective inhibitors of proinflammatory cytokines. SOLUTION: The inhibitors are provided by using new 9-N-bicyclic nucleoside compound, i.e, a compound of the formula or a pharmaceutically permissible salt thereof. (Wherein, Y is N or CH; Z1and Z2are each H, a halogen or NH2; and X is N3, NH2and the like.). COPYRIGHT: (C)2005,JPO&NCIPI