OPTICALLY ACTIVE COMPOUND OF MESYLATE TRIHYDRATE SALT OF 1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDIN-1-YL)-1-PROPANOL

PROBLEM TO BE SOLVED: To provide a optically active compound of mesylate trihydrate salt of (1S,2S)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-propanol compound represented by formula (I). SOLUTION: The optically active substance of the compound is produced by a method for producing...

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Hauptverfasser:	SINAY TERRY GENE JR, WALINSKY STANLEY WALTER, RAINVILLE JOSEPH PHILIP
Format:	Patent
Sprache:	eng
Schlagworte:	APPARATUS THEREFOR CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a optically active compound of mesylate trihydrate salt of (1S,2S)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-propanol compound represented by formula (I). SOLUTION: The optically active substance of the compound is produced by a method for producing mesylate trihydrate salt of a compound represented by formula (I), wherein the method comprises steps of (i) dissolving D-(-)-tartrate salt of a compound represented by formula (I) in an aqueous solution of methanesulfonic acid and (ii) separating the methanesulfonate trihydrate from the solution. COPYRIGHT: (C)2004,JPO&NCIPI