PHYSIOLOGICALLY ACTIVE NEW PEPTIDE AND ITS USE

PROBLEM TO BE SOLVED: To obtain a useful mouse homolog ligand for human being-derived ligand (WO 99/48920) specific to galanin receptor. SOLUTION: This mouse homolog ligand comprises a peptide, its precursor, its amide, its ester or its salt which contains the amino acid sequence homologous or subst...

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Hauptverfasser: OTAKI TETSUYA, KUMANO SATOSHI
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KUMANO SATOSHI
description PROBLEM TO BE SOLVED: To obtain a useful mouse homolog ligand for human being-derived ligand (WO 99/48920) specific to galanin receptor. SOLUTION: This mouse homolog ligand comprises a peptide, its precursor, its amide, its ester or its salt which contains the amino acid sequence homologous or substantially homologous to a mouse-derived specific amino acid sequence and the amino acid sequence homologous or substantially homologous to either of three kinds of rat-derived specific amino acid sequences and exhibits an ability of combining with a galanin receptor protein. The DNA or the like encoding the peptide can be used for (i) the development of a receptor-bound assay system using a recombinant receptor protein expression system and the screening of a compound being considered for medicine or (ii) the development or the like of a medicine, e.g. a mneme ameliorative agent, an aperitive or a function regulator on uterus, ren, prostate, testis or skeletal muscle, having slight adverse drug reactions.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
TESTING
VINEGAR
WINE
title PHYSIOLOGICALLY ACTIVE NEW PEPTIDE AND ITS USE
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