METHOD AND DEVICE FOR CALCULATING OPTIMUM SOLUTION OF MULTIPLEX VARIATION PROTEIN AMINO ACID ARRAY AND STORAGE MEDIUM STORING PROGRAM FOR CONDUCTING THE SAME
PROBLEM TO BE SOLVED: To select an optimum solution based on a feature value in short time without deteriorating precision from a multiplex variation protein group whose number of combinations is huge. SOLUTION: A method for calculating the optimum solution of a multiplex variation protein amino aci...
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creator | NAKAI TAKANAO ISHII KIYOTO MORIKAWA SOICHI |
description | PROBLEM TO BE SOLVED: To select an optimum solution based on a feature value in short time without deteriorating precision from a multiplex variation protein group whose number of combinations is huge. SOLUTION: A method for calculating the optimum solution of a multiplex variation protein amino acid array includes a step for calculating the optimum stereoscopic structure coordinate of multiplex variation protein by searching the amino acid side chain stereoscopic structure coordinate of the respective amino acid arrays in a member by using a dead end elimination algorithm based on stereoscopic structure data of a model protein group with respect to the member of the multiplex variation protein group and by conducting the structure energy minimizing calculation of the member, a step for calculating the feature value from the optimum stereoscopic structure coordinate of optimum multiplex variation protein and a step for calculating the member optimizing the feature value by applying genetic algorithm to the multiplex variation protein group. |
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SOLUTION: A method for calculating the optimum solution of a multiplex variation protein amino acid array includes a step for calculating the optimum stereoscopic structure coordinate of multiplex variation protein by searching the amino acid side chain stereoscopic structure coordinate of the respective amino acid arrays in a member by using a dead end elimination algorithm based on stereoscopic structure data of a model protein group with respect to the member of the multiplex variation protein group and by conducting the structure energy minimizing calculation of the member, a step for calculating the feature value from the optimum stereoscopic structure coordinate of optimum multiplex variation protein and a step for calculating the member optimizing the feature value by applying genetic algorithm to the multiplex variation protein group.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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subjects | BEER BIOCHEMISTRY CALCULATING CHEMISTRY COMPOSITIONS THEREOF COMPUTING COUNTING CULTURE MEDIA ELECTRIC DIGITAL DATA PROCESSING ENZYMOLOGY INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
title | METHOD AND DEVICE FOR CALCULATING OPTIMUM SOLUTION OF MULTIPLEX VARIATION PROTEIN AMINO ACID ARRAY AND STORAGE MEDIUM STORING PROGRAM FOR CONDUCTING THE SAME |
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