SULFONAMIDE DERIVATIVE AND AGENT CONTAINING THE DERIVATIVE AS ACTIVE COMPONENT
PROBLEM TO BE SOLVED: To provide a new sulfonamide derivative useful as an active component for prostaglandin E2 antagonistic or agonistic agent. SOLUTION: The objective compound is expressed by formula I [a group of formula II is a 5 to 7-membered heterocyclic group having a 5-7C carbon ring, O, S...
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| creator | OUCHIDA SHUICHI NAGAO HISAKI |
| description | PROBLEM TO BE SOLVED: To provide a new sulfonamide derivative useful as an active component for prostaglandin E2 antagonistic or agonistic agent. SOLUTION: The objective compound is expressed by formula I [a group of formula II is a 5 to 7-membered heterocyclic group having a 5-7C carbon ring, O, S and N; Z1 is COR1 (R1 is OH or the like) or the like; Z2 is a 1-8C alkyl, a 2-8C alkenyl or the like; Z3 is single bond or a 1-4C alkylene; Z4 is SO2; Z5 is a 1-8C alkyl, phenyl or the like; R2 is CONR8 (R8 is H or a 1-4C alkyl), NR8CO or the like; R3 is a 1-6C alkyl, a halogen or the like; R4 is a 1-8C alkyl or the like; (n) is 1-4], e.g. 5-[5-chloro-2-(phenylsulfonylamino)phenoxy] pentaonic acid. The compound of formula I wherein Z1 is e.g. COOH can be produced by the hydrolysis of an ester compound of formula III [Z1b is COR1b (R1b is a 1-4C alkoxy or the like); R3b is R3; R4b is R4; Z5b is Z5, provided that Z5b is COOH or OH protected with an eliminable protecting group when R5 is COOH, OH or the like]. |
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| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_JP2000007646A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>JP2000007646A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_JP2000007646A3</originalsourceid><addsrcrecordid>eNrjZPALDvVx8_dz9PV0cVVwcQ3yDHMM8QxzVXD0c1FwdHf1C1Fw9vcLcfT08_RzVwjxQFUTrODoDGY5-_sG-PsBVfMwsKYl5hSn8kJpbgYlN9cQZw_d1IL8-NTigsTk1LzUknivACMDEDA3MzFzNCZKEQB0eS7o</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>SULFONAMIDE DERIVATIVE AND AGENT CONTAINING THE DERIVATIVE AS ACTIVE COMPONENT</title><source>esp@cenet</source><creator>OUCHIDA SHUICHI ; NAGAO HISAKI</creator><creatorcontrib>OUCHIDA SHUICHI ; NAGAO HISAKI</creatorcontrib><description>PROBLEM TO BE SOLVED: To provide a new sulfonamide derivative useful as an active component for prostaglandin E2 antagonistic or agonistic agent. SOLUTION: The objective compound is expressed by formula I [a group of formula II is a 5 to 7-membered heterocyclic group having a 5-7C carbon ring, O, S and N; Z1 is COR1 (R1 is OH or the like) or the like; Z2 is a 1-8C alkyl, a 2-8C alkenyl or the like; Z3 is single bond or a 1-4C alkylene; Z4 is SO2; Z5 is a 1-8C alkyl, phenyl or the like; R2 is CONR8 (R8 is H or a 1-4C alkyl), NR8CO or the like; R3 is a 1-6C alkyl, a halogen or the like; R4 is a 1-8C alkyl or the like; (n) is 1-4], e.g. 5-[5-chloro-2-(phenylsulfonylamino)phenoxy] pentaonic acid. The compound of formula I wherein Z1 is e.g. COOH can be produced by the hydrolysis of an ester compound of formula III [Z1b is COR1b (R1b is a 1-4C alkoxy or the like); R3b is R3; R4b is R4; Z5b is Z5, provided that Z5b is COOH or OH protected with an eliminable protecting group when R5 is COOH, OH or the like].</description><edition>7</edition><language>eng</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS ; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC ; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS ; TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE</subject><creationdate>2000</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20000111&DB=EPODOC&CC=JP&NR=2000007646A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20000111&DB=EPODOC&CC=JP&NR=2000007646A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>OUCHIDA SHUICHI</creatorcontrib><creatorcontrib>NAGAO HISAKI</creatorcontrib><title>SULFONAMIDE DERIVATIVE AND AGENT CONTAINING THE DERIVATIVE AS ACTIVE COMPONENT</title><description>PROBLEM TO BE SOLVED: To provide a new sulfonamide derivative useful as an active component for prostaglandin E2 antagonistic or agonistic agent. SOLUTION: The objective compound is expressed by formula I [a group of formula II is a 5 to 7-membered heterocyclic group having a 5-7C carbon ring, O, S and N; Z1 is COR1 (R1 is OH or the like) or the like; Z2 is a 1-8C alkyl, a 2-8C alkenyl or the like; Z3 is single bond or a 1-4C alkylene; Z4 is SO2; Z5 is a 1-8C alkyl, phenyl or the like; R2 is CONR8 (R8 is H or a 1-4C alkyl), NR8CO or the like; R3 is a 1-6C alkyl, a halogen or the like; R4 is a 1-8C alkyl or the like; (n) is 1-4], e.g. 5-[5-chloro-2-(phenylsulfonylamino)phenoxy] pentaonic acid. The compound of formula I wherein Z1 is e.g. COOH can be produced by the hydrolysis of an ester compound of formula III [Z1b is COR1b (R1b is a 1-4C alkoxy or the like); R3b is R3; R4b is R4; Z5b is Z5, provided that Z5b is COOH or OH protected with an eliminable protecting group when R5 is COOH, OH or the like].</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS</subject><subject>GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC</subject><subject>GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS</subject><subject>TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2000</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPALDvVx8_dz9PV0cVVwcQ3yDHMM8QxzVXD0c1FwdHf1C1Fw9vcLcfT08_RzVwjxQFUTrODoDGY5-_sG-PsBVfMwsKYl5hSn8kJpbgYlN9cQZw_d1IL8-NTigsTk1LzUknivACMDEDA3MzFzNCZKEQB0eS7o</recordid><startdate>20000111</startdate><enddate>20000111</enddate><creator>OUCHIDA SHUICHI</creator><creator>NAGAO HISAKI</creator><scope>EVB</scope></search><sort><creationdate>20000111</creationdate><title>SULFONAMIDE DERIVATIVE AND AGENT CONTAINING THE DERIVATIVE AS ACTIVE COMPONENT</title><author>OUCHIDA SHUICHI ; NAGAO HISAKI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_JP2000007646A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2000</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS</topic><topic>GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC</topic><topic>GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS</topic><topic>TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE</topic><toplevel>online_resources</toplevel><creatorcontrib>OUCHIDA SHUICHI</creatorcontrib><creatorcontrib>NAGAO HISAKI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>OUCHIDA SHUICHI</au><au>NAGAO HISAKI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SULFONAMIDE DERIVATIVE AND AGENT CONTAINING THE DERIVATIVE AS ACTIVE COMPONENT</title><date>2000-01-11</date><risdate>2000</risdate><abstract>PROBLEM TO BE SOLVED: To provide a new sulfonamide derivative useful as an active component for prostaglandin E2 antagonistic or agonistic agent. SOLUTION: The objective compound is expressed by formula I [a group of formula II is a 5 to 7-membered heterocyclic group having a 5-7C carbon ring, O, S and N; Z1 is COR1 (R1 is OH or the like) or the like; Z2 is a 1-8C alkyl, a 2-8C alkenyl or the like; Z3 is single bond or a 1-4C alkylene; Z4 is SO2; Z5 is a 1-8C alkyl, phenyl or the like; R2 is CONR8 (R8 is H or a 1-4C alkyl), NR8CO or the like; R3 is a 1-6C alkyl, a halogen or the like; R4 is a 1-8C alkyl or the like; (n) is 1-4], e.g. 5-[5-chloro-2-(phenylsulfonylamino)phenoxy] pentaonic acid. The compound of formula I wherein Z1 is e.g. COOH can be produced by the hydrolysis of an ester compound of formula III [Z1b is COR1b (R1b is a 1-4C alkoxy or the like); R3b is R3; R4b is R4; Z5b is Z5, provided that Z5b is COOH or OH protected with an eliminable protecting group when R5 is COOH, OH or the like].</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE |
| title | SULFONAMIDE DERIVATIVE AND AGENT CONTAINING THE DERIVATIVE AS ACTIVE COMPONENT |
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