DERIVATO FOSFOLIPIDICO DOTATO DI AZIONE ANTILIPEMICA E ANTIARTERIOSCLEROTICA

DERIVATO FOSFOLIPIDICO DOTATO DI AZIONE ANTILIPEMICA E ANTIARTERIOSCLEROTICA

New phosphatidylethanolamine N-oleyl derivs. are of formula (I): In (I), R1 and R2 are the residues of 12-22C fatty acids (pref. natural) which may be satd. or unsatd. (contg. >=1 double bonds) and be branched or unbranched. (I) have anti-arteriosclerotic and antilipaemic activity after oral admi...

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Bibliographische Detailangaben
Hauptverfasser: BETZING HANS, DAWIDSON HERBERT
Format: Patent
Sprache:ita
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:New phosphatidylethanolamine N-oleyl derivs. are of formula (I): In (I), R1 and R2 are the residues of 12-22C fatty acids (pref. natural) which may be satd. or unsatd. (contg. >=1 double bonds) and be branched or unbranched. (I) have anti-arteriosclerotic and antilipaemic activity after oral admin. In experiments in rats, 1 mg./kg. gives marked lowering of total lipids, esp. cholesterol and triglycerides, in serum.