COMPOSIZIONE FARMACEUTICA CHE COMPRENDE UNA PARTICOLARE FORMA FISICA DI UN DERIVATO DI UN'AMMIDE ETEROCICLICA

L'invenzione mette a disposizione una composizione farmaceutica che comprende una particolare forma fisica di N-[4-[5-(ciclopentilossicarbonil)-ammino-1-metilindol-3-il-metil]-3-metossibenzoil]-2-metil-benzensolfonammide e di polivinilpirrolidone. Essa inoltre mette a disposizione metodi per pr...

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Hauptverfasser:	CLEMENTS ARLENE, TIMKO ROBERT JOSEP, BRADWAY RANDY JOHN, HOLOHAN JAMES JOSEPH, EDWARDS IEUAN JOHN
Format:	Patent
Sprache:	ita
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	CLEMENTS ARLENE TIMKO ROBERT JOSEP BRADWAY RANDY JOHN HOLOHAN JAMES JOSEPH EDWARDS IEUAN JOHN
description	L'invenzione mette a disposizione una composizione farmaceutica che comprende una particolare forma fisica di N-[4-[5-(ciclopentilossicarbonil)-ammino-1-metilindol-3-il-metil]-3-metossibenzoil]-2-metil-benzensolfonammide e di polivinilpirrolidone. Essa inoltre mette a disposizione metodi per preparare questa forma fisica e un'altra forma fisica di N-[4-[5-(ciclopentilossicarbonil)-ammino-1-metilindol-3-il-metil]-3-metossibenzoil]-2-metil-benzensolfonammide utile nella preparazione della forma fisica citata per prima. Le composizioni sono utili nel trattamento di malattie nelle quali sono implicati leucotrieni, per esempio l'asma. The invention provides a pharmaceutical composition comprising a particular physical form of N-[4-[5-(cyclopentyloxycarbonyl)amino-1-methylindol-3-yl-methyl]-3-met hoxybenzoyl]-2-methylbenzenesulphonamide and polyvinylpyrrolidone. It also provides methods for preparing this physical form, and another physical form of N-[4-[5-(cyclopentyloxycarbonyl)amino-1-methylindol-3-yl-methyl]-3-met hoxybenzoyl]-2-methylbenzenesulphonamide useful in the preparation of the first mentioned physical form. The compositions are useful in the treatment of diseases in which leukotrienes are implicated, for example asthma.
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Essa inoltre mette a disposizione metodi per preparare questa forma fisica e un'altra forma fisica di N-[4-[5-(ciclopentilossicarbonil)-ammino-1-metilindol-3-il-metil]-3-metossibenzoil]-2-metil-benzensolfonammide utile nella preparazione della forma fisica citata per prima. Le composizioni sono utili nel trattamento di malattie nelle quali sono implicati leucotrieni, per esempio l'asma. The invention provides a pharmaceutical composition comprising a particular physical form of N-[4-[5-(cyclopentyloxycarbonyl)amino-1-methylindol-3-yl-methyl]-3-met hoxybenzoyl]-2-methylbenzenesulphonamide and polyvinylpyrrolidone. It also provides methods for preparing this physical form, and another physical form of N-[4-[5-(cyclopentyloxycarbonyl)amino-1-methylindol-3-yl-methyl]-3-met hoxybenzoyl]-2-methylbenzenesulphonamide useful in the preparation of the first mentioned physical form. 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Essa inoltre mette a disposizione metodi per preparare questa forma fisica e un'altra forma fisica di N-[4-[5-(ciclopentilossicarbonil)-ammino-1-metilindol-3-il-metil]-3-metossibenzoil]-2-metil-benzensolfonammide utile nella preparazione della forma fisica citata per prima. Le composizioni sono utili nel trattamento di malattie nelle quali sono implicati leucotrieni, per esempio l'asma. The invention provides a pharmaceutical composition comprising a particular physical form of N-[4-[5-(cyclopentyloxycarbonyl)amino-1-methylindol-3-yl-methyl]-3-met hoxybenzoyl]-2-methylbenzenesulphonamide and polyvinylpyrrolidone. It also provides methods for preparing this physical form, and another physical form of N-[4-[5-(cyclopentyloxycarbonyl)amino-1-methylindol-3-yl-methyl]-3-met hoxybenzoyl]-2-methylbenzenesulphonamide useful in the preparation of the first mentioned physical form. The compositions are useful in the treatment of diseases in which leukotrienes are implicated, for example asthma.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record>
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subjects	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	COMPOSIZIONE FARMACEUTICA CHE COMPRENDE UNA PARTICOLARE FORMA FISICA DI UN DERIVATO DI UN'AMMIDE ETEROCICLICA
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