ALCANOILANILIDI

( omega )-[4-(2-pyridyl)-piperazino]-alkanoylanilide derivatives of the general formula I are provided. In the formula, n = 1, 2 or 3, each of R, R1, R2, R3 and R4 is independently H, halogen, alkyl, alkoxy, OH, NH2, CF3, CN, alkylthio, 1-hydroxyalkyl, alkanoyl, NH2CO, NH2SO2, alkoxycarbonyl, alkyls...

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Hauptverfasser: DANTE NARDI, ALBERTO TAJANA, GABRIELE GRAZIANI, ALBERTO CATTO, PIETRO CAZZULANI
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creator DANTE NARDI
ALBERTO TAJANA
GABRIELE GRAZIANI
ALBERTO CATTO
PIETRO CAZZULANI
description ( omega )-[4-(2-pyridyl)-piperazino]-alkanoylanilide derivatives of the general formula I are provided. In the formula, n = 1, 2 or 3, each of R, R1, R2, R3 and R4 is independently H, halogen, alkyl, alkoxy, OH, NH2, CF3, CN, alkylthio, 1-hydroxyalkyl, alkanoyl, NH2CO, NH2SO2, alkoxycarbonyl, alkylsulphonyl, benzyloxy, alkanoylamino, NH2CONH, 3-phenylureido, 3-alkylureido or alkoxyoxalylamino, R5 = H or alkyl, R6 = H or alkoxy. These compounds and their pharmaceutically acceptable salts have antianaphylactic, antibronchospastic, antihistaminic, sedative, analgesic, antiserotonic and blood-pressure-lowering effects. Their preparation and pharmaceutical compositions containing them are disclosed.
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In the formula, n = 1, 2 or 3, each of R, R1, R2, R3 and R4 is independently H, halogen, alkyl, alkoxy, OH, NH2, CF3, CN, alkylthio, 1-hydroxyalkyl, alkanoyl, NH2CO, NH2SO2, alkoxycarbonyl, alkylsulphonyl, benzyloxy, alkanoylamino, NH2CONH, 3-phenylureido, 3-alkylureido or alkoxyoxalylamino, R5 = H or alkyl, R6 = H or alkoxy. These compounds and their pharmaceutically acceptable salts have antianaphylactic, antibronchospastic, antihistaminic, sedative, analgesic, antiserotonic and blood-pressure-lowering effects. 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Their preparation and pharmaceutical compositions containing them are disclosed.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1992</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZOB39HF29PP39HH08_TxdPHkYWBNS8wpTuWF0twM8m6uIc4euqkF-fGpxQWJyal5qSXxniGGRsZGZgamTsaEVQAAd7Ycbw</recordid><startdate>19920228</startdate><enddate>19920228</enddate><creator>DANTE NARDI</creator><creator>ALBERTO TAJANA</creator><creator>GABRIELE GRAZIANI</creator><creator>ALBERTO CATTO</creator><creator>PIETRO CAZZULANI</creator><scope>EVB</scope></search><sort><creationdate>19920228</creationdate><title>ALCANOILANILIDI</title><author>DANTE NARDI ; ALBERTO TAJANA ; GABRIELE GRAZIANI ; ALBERTO CATTO ; PIETRO CAZZULANI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_IT1232605B3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>ita</language><creationdate>1992</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>DANTE NARDI</creatorcontrib><creatorcontrib>ALBERTO TAJANA</creatorcontrib><creatorcontrib>GABRIELE GRAZIANI</creatorcontrib><creatorcontrib>ALBERTO CATTO</creatorcontrib><creatorcontrib>PIETRO CAZZULANI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DANTE NARDI</au><au>ALBERTO TAJANA</au><au>GABRIELE GRAZIANI</au><au>ALBERTO CATTO</au><au>PIETRO CAZZULANI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ALCANOILANILIDI</title><date>1992-02-28</date><risdate>1992</risdate><abstract>( omega )-[4-(2-pyridyl)-piperazino]-alkanoylanilide derivatives of the general formula I are provided. 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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title ALCANOILANILIDI
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