[(PIRIDINIL)-2-PIRIMIDINIL]UREE UTILI COME CARDIOTONICI E LORO PREPARAZIONE

[(PIRIDINIL)-2-PIRIMIDINIL]UREE UTILI COME CARDIOTONICI E LORO PREPARAZIONE

N-R-N'-R'-N-[4(or 5)-PY-2-pyrimidinyl]ureas (I) or salts thereof, where PY is 4- or 3-pyridinyl or 4- or 3-pyridinyl having one or two lower-alkyl substituents, R' is hydrogen or methyl and R is methyl or ethyl when PY is attached to the 4-position of the pyrimidine ring or R is hydro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GEORGE YOHE LESHER, BALDEV SINGH
Format: Patent
Sprache:ita
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:N-R-N'-R'-N-[4(or 5)-PY-2-pyrimidinyl]ureas (I) or salts thereof, where PY is 4- or 3-pyridinyl or 4- or 3-pyridinyl having one or two lower-alkyl substituents, R' is hydrogen or methyl and R is methyl or ethyl when PY is attached to the 4-position of the pyrimidine ring or R is hydrogen, ethyl or n-butyl when PY is attached to the 5-position of the pyrimidine ring are useful as cardiotonic agents. The preparations of I and their cardiotonic use are shown.