COLECALCIFEROL-DERIVATI

The syntheses of 25,26-dehydro-1 alpha ,24R-dihydroxycholecalciferol and 25,26-dehydro-1 alpha ,24S-dihydroxycholecalciferol and the epimeric mixture which are useful as differentiation inducing agent and anti-proliferation agents are described. 25,26-dehydro-1 alpha ,24R-dihydroxycholecalciferol, 2...

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Hauptverfasser:	SHIAN JAN SHIUEY, MILAN RADOJE USKOKOVIC, GARY ARTHUR TRUITT, JOHN JOSEPH PATRIDGE
Format:	Patent
Sprache:	ita
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	The syntheses of 25,26-dehydro-1 alpha ,24R-dihydroxycholecalciferol and 25,26-dehydro-1 alpha ,24S-dihydroxycholecalciferol and the epimeric mixture which are useful as differentiation inducing agent and anti-proliferation agents are described. 25,26-dehydro-1 alpha ,24R-dihydroxycholecalciferol, 25,26-dehydro-1 alpha ,24S-dihydroxycholecalciferol, and the epimeric mixture are useful in treating osteoporosis, tumors and leukemia.